9 citations
,
January 2018 in “Acta dermato-venereologica” This study found that carbonic anhydrase II was significantly upregulated in human keratinocytes when treated with toll-like receptor 3 agonist and Th2 cytokines, suggesting its potential role in inflammatory skin conditions.
2 citations
,
July 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” This review discusses the role of hair follicles in wound healing and scar remodeling, emphasizing that hair follicle transplantation may aid in faster wound closure and scar reduction by enhancing the cellular and molecular mechanisms involved in scarring.
1 citations
,
November 2024 in “Journal of Plastic and Reconstructive Surgery” This study highlights the historical and contemporary use of hair sutures in plastic surgery, noting their advantages such as favorable aesthetic outcomes, minimal tissue reaction, and cost-effectiveness, despite modern synthetic alternatives.
1 citations
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January 2024 in “Advanced science” This study found that fibronectin-attached cell sheets significantly improved wound healing in vivo by increasing wound closure rates, reducing inflammation, and promoting tissue regeneration compared to conventional cell sheets.
August 2025 in “Materials Today Bio” This study reports that novel nanofibrous dressings combining polylysine and tannic acid significantly reduce bacterial burden, support wound healing, and exhibit strong anti-inflammatory effects in infected full-thickness wounds, promoting near-complete closure and skin regeneration within two weeks.
June 2025 in “Materials Today Bio” In diabetic mice, this study reported that the multifunctional hydrogel CPGel achieved complete wound closure in 21 days, showing promise in improving chronic wound healing through antibacterial, antioxidative, and tissue regeneration properties.
June 2025 in “Food Science & Nutrition” This study found that peimine treatment significantly improved wound healing and tissue regeneration in mice by enhancing wound closure, granulation tissue formation, and epidermal thickness, with effects linked to activation of the Notch1 signaling pathway.
June 2020 in “Journal of Investigative Dermatology” This study found that increasing commensal bacterial load on the skin enhances wound-induced hair follicle neogenesis in mice, mediated through IL1R-MyD88 signaling pathways.
16 citations
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July 2006 in “International Journal of Oral and Maxillofacial Surgery” This case report highlights the successful use of the Bardach modification of the curved tripod flap for repairing cicatricial pressure alopecia, offering a natural appearance and effective tension distribution in scalp reconstruction.
1 citations
,
July 2012 in “Springer eBooks” The document concludes that more research is needed to better understand and treat scarring hair loss conditions.
January 2025 in “Medicina” This study reviews emerging techniques in acute burn wound therapy, noting innovations such as advanced imaging for better wound assessment and new closure strategies aimed at improving healing, graft survival, and scarring outcomes, while emphasizing the need for further research to validate these methods.
16 citations
,
September 2016 in “Neuropharmacology” This study suggests that in an ex vivo rat glaucoma model, TSPO activation is involved in Allopregnanolone synthesis and may help prevent retinal damage, with TSPO agonists as potential therapeutic agents.
1 citations
,
January 2018 in “Indian journal of otolaryngology and head and neck surgery” This case study details an elderly patient with multiple nasal vestibular furunculosis leading to severe tissue damage and a nasolabial fistula, which was addressed using an alar advancement flap after allowing for tissue healing.
September 2023 in “Clinical, cosmetic and investigational dermatology” This case series reports successful treatment of refractory folliculitis decalvans using surgical excision with second-intention healing and guarded high-tension suturing, resulting in long-term remission without recurrence over a 10–24 month follow-up period.
829 citations
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May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
86 citations
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March 2018 in “ACS Biomaterials Science & Engineering” This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.
46 citations
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September 2013 in “PLOS ONE” This study identified thyrotropin-releasing hormone (TRH) as a stimulant of wound healing in both frog and human skin models, suggesting it as a potential neuroendocrine wound repair promoter.
33 citations
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September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that human hair follicle dermal cells, specifically dermal sheath cells, can serve as an alternative and potentially superior cell source for constructing the dermal component of bioengineered skin in both in vitro and in vivo settings.
33 citations
,
September 2012 in “Wound Repair and Regeneration” This study found that the application of calreticulin significantly improved wound healing time and quality in diabetic mice, suggesting it may be an effective topical treatment for chronic wounds.
31 citations
,
December 2021 in “Materials” In a study using a mouse model of diabetes, chitosan-based hydrogels increased healing markers and improved wound closure and tissue repair compared to untreated wounds, but human efficacy needs further validation.
28 citations
,
December 2018 in “Plant, cell & environment/Plant, cell and environment” This study found that the PLC2 gene plays a critical role in auxin-mediated root development in Arabidopsis, influencing root growth and PIN2 distribution.
24 citations
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August 2020 in “JAMA dermatology” In this study, researchers observed a dose-dependent occurrence of persistent radiation-induced alopecia in patients with primary CNS tumors or head and neck sarcomas, noting distinctive patterns and features, and suggesting potential benefits of topical minoxidil and procedural interventions for treatment.
24 citations
,
July 2019 in “Reproductive Medicine and Biology” This review discusses the classification and treatment of ejaculatory dysfunction, outlining both pharmacotherapy and behavioral therapy as primary interventions, but does not present new clinical findings.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” This review discusses hair follicle stem cells for wound healing and reports no new clinical results, noting their potential but emphasizing the need for further understanding and safety in clinical applications.
14 citations
,
April 2023 in “International Journal of Molecular Sciences” In a study using female Wistar rats, the researchers found that a liquid allantoin-enriched pectin hydrogel significantly improved wound healing, achieving a 71.43% reduction in healing time and complete wound closure in 15 days.
13 citations
,
March 2022 in “Cell Death and Differentiation” This study found that while autonomous Sema3A expression limited keratinocyte migration and delayed wound healing, non-autonomous application of recombinant Sema3A with EGF enhanced wound repair in mice.
9 citations
,
April 2024 in “Cureus” This study outlines the features and diagnosis of Vogt-Koyanagi-Harada disease, highlighting its association with specific genes, its prevalence among pigmented races, and treatment with systemic steroids and immunosuppressants.
8 citations
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August 2023 in “Journal of Investigative Dermatology” This study reported that in a mouse tail wound model, the synthetic dual inhibitor corin accelerated wound closure by enhancing re-epithelialization, and further in vitro experiments demonstrated increased expression of genes promoting keratinocyte migration, suggesting its potential as a treatment for chronic wounds.
8 citations
,
December 1996 in “Dermatologic Surgery” This article discusses surgical innovations in scalp reduction to improve cosmetic outcomes but reports no new clinical results, emphasizing the benefits of anchor techniques for minimizing scars and stretch-back.
6 citations
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July 2023 in “Plants” This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.