May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated polyherbal formulations for managing hair issues such as dandruff, dryness, premature greying, baldness, and hair fall, but it reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study assesses the effectiveness of polyherbal formulations in managing hair issues such as dandruff, dryness, premature greying, baldness, and excessive hair fall, in response to increasing hair loss among younger individuals due to stress, poor diet, and chemical use.
14 citations
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April 2007 in “Journal of aging and health” This study observed that balding was associated with lower total body BMD in men and higher hip BMD in women, possibly due to estrogen use in the latter group.
12 citations
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April 2022 in “Frontiers in Cell and Developmental Biology” This study found that stabilizing β-catenin in a specific mouse model led to temporarily increased hair density but ultimately accelerated hair follicle aging and hair thinning.
126 citations
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January 2009 in “International Journal of Trichology” This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.
January 2024 in “International journal of Indian medicine” In this article, the authors aimed to educate readers on common hair disorders linked to improper care, emphasizing prevention and treatment using Ayurvedic principles such as Dincharya and yoga.
February 2020 in “Scholars international journal of traditional and complementary medicine” This article explores Ayurvedic approaches to treating hair disorders and provides no new clinical results, highlighting practices like using herbal treatments for hair loss and greying.
April 2026 in “BMC Women s Health” This study in Urmia, Iran, characterized women with PCOS, POF, and EMs, revealing a PCOS prevalence of 17.69% and emphasizing significant lifestyle and health differences compared to healthy individuals, particularly in rural areas, alongside identifying key screening features for POF and EMs.
December 2024 in “International Journal Of Ayurvedic And Herbal Medicine” This review highlights Shirodhara's potential cosmetic benefits, noting improvements in scalp health, hair growth, and skin appearance, attributed to stress reduction, hormonal balance, enhanced circulation, and nutrient-rich herbal oils.
September 2022 in “International Journal of Health Sciences (IJHS)” This study examined the relationship between zinc status and DNA oxidative damage in patients with hair loss in Duhok, Kurdistan Region-Iraq, highlighting the potential role of zinc deficiency in hair loss.
July 2024 in “Journal of Investigative Dermatology” Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.
December 2021 in “Molecular genetics and genomics” This study found that two unrelated domestic shorthair cats had novel DSG4 gene mutations causing defective hair shafts, representing the first report of pathogenic DSG4 variants in domestic animals.
This article reviews current understanding of Hutchinson–Gilford Progeria Syndrome and suggests RNA-based treatments show promise, but no new clinical findings are reported.
27 citations
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January 2002 in “Exogenous Dermatology” In this study, researchers reported that chronic UV exposure may contribute to androgenic alopecia progression by influencing hair cycle changes and exacerbating solar elastosis in the scalp.
18 citations
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November 2016 in “Neuromuscular Disorders” This study found that patients with myotonic dystrophy types 1 and 2 often exhibit skin abnormalities, which correlate with genotype severity and serum vitamin D levels, and suggest premature aging.
4 citations
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December 2020 in “Journal of Dermatology” This study suggests that impaired autophagy may be a potential mechanism contributing to androgenetic alopecia, as observed in miniaturized hair follicles from balding scalps.
This study found that miR-22 regulates hair loss in mice by causing premature regression of hair follicles and suggests the importance of the microRNA regulatory network in understanding hair cycling and loss.
67 citations
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August 2007 in “American Journal of Pathology” This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.
194 citations
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March 2003 in “American Journal of Pathology” This study found that psychoemotional stress disrupts hair growth in mice by terminating anagen and suggests a potential pathway for pharmacological management of stress-related hair loss in humans.
August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This review discusses the effects of mineralocorticoid receptor overexpression in mice skin, reporting no new data but highlighting its link to epidermal atrophy, early barrier formation, eye issues, and hair loss.
5 citations
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July 2016 in “Experimental Dermatology” This article reviews the limitations in current research on photobiomodulation for hair regrowth and suggests that optimal wavelengths and dosing have not yet been identified, noting that recommending these devices may be premature.
January 2018 in “Biomedical Research (Aligarh)” This study found no significant differences in bone mineral density or predisposing factors across hair-loss stages in women with androgenetic alopecia, though early-onset cases may warrant investigation for premature bone loss.
39 citations
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January 2004 in “Physiological Research” In this study, researchers reported that about one-third of men with premature alopecia displayed hormonal shifts and higher insulin resistance, resembling the prevalence pattern of PCOS in women.
35 citations
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January 1993 in “International Journal of Dermatology” In this study, most hair disorders among HIV-1 positive patients were associated with low helper T cell counts, with papulosquamous conditions like seborrheic dermatitis and psoriasis being the most common.
November 2024 in “International Journal of Women’s Dermatology” In this study of a Colombian sample, the researchers found that while sex, alopecia location, and symptoms aligned with global reports, age at presentation, tobacco use, and use of wigs and dyes were different from those noted in other countries.
April 2012 in “Informa Healthcare eBooks” The document concludes that diagnosing hair loss requires evaluating multiple histological features, as no single feature is definitive on its own.
September 2002 in “Fertility and sterility” This study found that hirsutism is more frequent among female relatives of PCOS patients, suggesting a hereditary aspect of PCOS, while premature balding was not more common among male relatives.
December 2024 in “Journal of Clinical Research in Pediatric Endocrinology” This study explains that congenital adrenal hyperplasia due to 21-hydroxylase deficiency presents as a continuous phenotype and involves symptoms ranging from virilization to accelerated growth in children, with diagnosis relying on clinical, biochemical, and genetic evaluation.
114 citations
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February 2012 in “International Journal of Dermatology” This review examines the dermatologic effects of tobacco use and nicotine, noting potential benefits and drawbacks for various skin conditions, but reports no new clinical results.
3 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.