March 2014 in “Journal of The American Academy of Dermatology” Mycophenolic acid may help hair growth, a combination treatment improves hair thickness in male hair loss, and early treatment of frontal fibrosing alopecia is important.
January 2014 in “CyberLeninK (CyberLeninka)” This article reviews office treatments for common cosmetic issues, including management techniques for benign lesions and procedures for acne scarring and hair loss, but reports no new clinical results.
May 2013 in “Springer eBooks” Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
January 2013 in “International Journal of Trichology” This case report highlights the discovery of a novel TRPS1 gene mutation in a 17-year-old with TRPS type I, underscoring the diagnostic importance of hair symptoms in congenital hair diseases.
April 2012 in “Informa Healthcare eBooks” The document concludes that diagnosing hair loss requires evaluating multiple histological features, as no single feature is definitive on its own.
March 2012 in “Journal of the American Academy of Dermatology” Treating ovarian-related inflammation may help hair regrowth in women with alopecia areata.
November 2009 in “Journal of Pediatric Nursing” This case report describes a 6 1/2-year-old girl with significant height growth and early pubic hair development.
May 2009 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, a transgenic mouse model suggested that suppressing the expression of the HGPS mutation may reverse disease symptoms, including skin abnormalities, supporting the potential for treatment development.
January 2009 in “International Journal of Trichology” Dr. Shyam B Verma encourages more scientific research on hair disorders and criticizes the unscientific hair care market in India.
January 2008 in “Catalunya música: Revista musical catalana” In this animal study, researchers observed that tooth loss in young mice led to premature gray hair growth in the interbrow area, likely due to reduced mastication affecting nerve input.
February 2005 in “Journal of The American Academy of Dermatology” This discussion covers various nail disorders, including tumors and non-neoplastic issues, emphasizing that not all nail abnormalities are due to fungal infections, but it reports no new clinical findings.
September 2002 in “Fertility and sterility” This study found that hirsutism is more frequent among female relatives of PCOS patients, suggesting a hereditary aspect of PCOS, while premature balding was not more common among male relatives.
January 2001 in “Cambridge University Press eBooks” This article discusses polycystic ovary syndrome (PCOS), its symptoms, and links to insulin resistance and type 2 diabetes, but reports no new research findings; the authors emphasize recognition of features in youth.
June 1995 in “International Journal of Gynecology & Obstetrics” This article provides citations without reporting new findings on androgen conjugate levels in alopecia.
This study found no significant difference in serum ferritin levels between individuals with androgenetic alopecia and healthy controls, but reported lower ferritin levels in those with premature alopecia compared to adult-onset cases.
February 2018 in “PubMed” In a survey of dermatologists, 88% reported an increase in male androgenetic alopecia incidence among men under 30, suggesting possible social or environmental influences on genetic risk factors.
December 2006 in “8th European Congress of Endocrinology incorporating the British Endocrine Societies” Men with early hair loss and hormonal changes like PCOS could be the male equivalent of PCOS, not linked to metabolic syndrome.
November 2024 in “Revista de Investigación y Educación en Ciencias de la Salud (RIECS)” In this case study, a 7-year-old girl was diagnosed with Isolated Premature Pubarche after presenting with pubic hair growth and normal hormonal and bone age assessments.
This study explored the potential of custard apple extract in an herbal hair conditioner to improve smoothness, aid brushing, and provide other cosmetic benefits, including lice removal and anti-aging effects.
8 citations
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January 2013 in “BioMed Research International” This study observed that both Factor XIIIa+ dermal dendrocytes and microvasculature size decreased with scalp aging and that alopecia changes resembled stress-induced premature senescence.
2 citations
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December 2025 in “Annals of Medicine” This review discusses the complex correlation between cellular senescence and PCOS, emphasizing senescence markers, mechanisms, and potential anti-senescence therapies, but reports no new clinical results.
76 citations
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March 2005 in “Journal of Molecular Medicine” This study found that premature hair loss due to stress does not occur in NK-1 receptor knockout or mast cell deficient mice, suggesting a key role for neurokinin substance P and mast cell interaction in stress-related hair follicle changes.
28 citations
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June 2007 in “Journal of Cutaneous Pathology” This study found that premature desquamation of the inner root sheath is a non-specific histologic feature in scarring alopecia and cannot be used alone to define central centrifugal cicatricial alopecia.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
4 citations
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March 2022 in “Ghana Medical Journal” This study found that hair greying is prevalent among adult traders in Lagos, Nigeria, typically onset at age 30, with premature greying considered uncommon.
3 citations
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February 2005 in “Aktuelle Dermatologie” This study found that prolactin can induce premature catagen in both mouse and human hair follicles and suggests that targeting prolactin and TGF-β receptors may be promising for treating androgenetic alopecia.
January 2014 in “International Journal of Clinical Medicine” This case report suggests that premature aging may contribute to weakened immunity and the development of autoimmune diseases.
53 citations
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January 2011 in “Diabetes” The study found that severe insulin resistance and premature diabetes are common in patients with PCNT genetic defects, primarily affecting those over four years old, while not impacting early insulin signaling in adipocytes.
45 citations
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June 2012 in “JRSM Cardiovascular Disease” In this study, premature coronary artery disease in Indians under 40 was linked to factors like dyslipidemia, low HDL-C, smoking, and central obesity, with cutaneous markers significantly associated.