14 citations
,
March 1995 in “Journal of cell science” This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.
13 citations
,
December 2017 in “Stem cells” This study found that in mice, low-dose irradiation causes stem cells in hair follicles to undergo chromatin alterations, which may eventually lead to long-term functional loss in tissues or organs.
12 citations
,
April 2022 in “Frontiers in Cell and Developmental Biology” This study found that stabilizing β-catenin in a specific mouse model led to temporarily increased hair density but ultimately accelerated hair follicle aging and hair thinning.
12 citations
,
September 2018 in “International Journal of Cosmetic Science” This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.
11 citations
,
May 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This review summarizes the phytomedicinal importance of Eclipta alba in Ayurvedic and folk medicine, particularly its use for hair growth and various biological properties, without reporting new clinical results.
11 citations
,
January 2016 in “Journal of clinical & experimental dermatology research” This review discusses the cutaneous manifestations associated with various substances of abuse, highlighting their importance for clinicians in recognizing and treating substance abuse disorders, and reports no new findings.
10 citations
,
March 2024 in “Endocrine Reviews” In this retrospective review, the author discusses key discoveries in understanding androgen excess disorders like PCOS, focusing on genetic and molecular insights gained from 1965 to 2015.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.
9 citations
,
February 2018 in “The Journal of Dermatology” This study identified a novel splice site mutation in the LIPH gene associated with autosomal recessive woolly hair, contributing to understanding the genetic basis of this condition.
8 citations
,
May 2003 in “Clinical and Experimental Dermatology” This case report suggests that nonsynchronized segmented heterochromia in black scalp hair in a 14-year-old girl may represent premature greying unrelated to deficiencies in iron, copper, zinc, or protein.
7 citations
,
December 2022 in “Plants” This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.
5 citations
,
January 2021 in “Skin appendage disorders” This review summarizes evidence suggesting that smoking is associated with alopecia and premature hair graying, with smokers showing higher prevalence than nonsmokers.
5 citations
,
February 2014 in “PubMed” This review discusses different types of telogen effluvium, highlighting that most cases seen by dermatologists are autoimmune-related, with stress as a triggering factor, and reports no new clinical findings.
5 citations
,
January 2012 in “Indian Journal of Dermatology Venereology and Leprology” Werner's syndrome causes early aging and increases cancer risk, requiring early diagnosis and symptom management.
4 citations
,
December 2022 in “Frontiers in Endocrinology” This review discusses various treatment options for non-classic congenital adrenal hyperplasia due to 21α-hydroxylase and 11β-hydroxylase deficiencies without providing new clinical results.
4 citations
,
May 2020 in “Cureus” This case report describes an adult male from India with Werner's syndrome due to a novel homozygous mutation in the WRN gene, characterized by several premature aging symptoms.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” This study suggests that 5-ADIOL-S may contribute to the synthesis of potent androgens in peripheral tissues, and 3 alpha-DIOL-S could be a marker of androgen metabolism in various female patient groups.
4 citations
,
November 1981 in “Indian Journal of Dermatology Venereology and Leprology” This study observed that oral calcium pantothenate may reverse hair greying in some adolescent cases, as seen in two girls whose grey hairs turned black after treatment.
3 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.
2 citations
,
March 2023 in “Journal of Nepal Medical Association” This study found that 40.42% of undergraduate medical students aged under 25 had early canities, with grade I being the most common.
2 citations
,
October 2022 in “International journal of Ayurvedic medicine” This review examines the traditional uses and biological activities of Glycyrrhiza glabra in Ayurveda, but reports no new clinical results; the authors identify a gap in evidence supporting its medicinal potential.
2 citations
,
June 2020 in “Journal of Drug Delivery and Therapeutics” This article discusses various hair-related issues, such as dandruff and hair loss, and outlines potential solutions, highlighting the need for personalized treatments and cost-effective approaches based on specific hair problems.
2 citations
,
April 2018 in “Journal of Investigative Dermatology” This study defines two types of RDEB wounds, chronic open and recurrent, and finds that patient self-reports on wound size correlate well with investigator measurements when complemented by serial photography.
2 citations
,
October 2017 in “Revista Da Associacao Medica Brasileira” The study found that silencing the gene p16INK4a in dermal papilla cells promotes their growth and aggregative behavior, suggesting a potential therapeutic target for androgenetic alopecia.
2 citations
,
September 2016 in “Journal of skin and stem cell” This study observed that acne was strongly associated with higher BMI, alopecia, menstrual dysfunction, positive familial history, and overuse of sweet and fatty foods among dermatology patients.
2 citations
,
May 2006 in “Women's Health Medicine” This article provides an overview of ovulation disorders, discussing ovarian, hypothalamic, and endocrine defects but reports no new clinical findings.
2 citations
,
January 2002 in “Clinics in Dermatology” This review details the characteristics, associations, and differential diagnoses of vitiligo and reports no new clinical findings.
1 citations
,
December 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review highlights that pediatric hirsutism, often linked to endocrine, metabolic, genetic, or neoplastic disorders, requires comprehensive evaluation to prevent long-term health issues, integrating advancements in androgen biosynthesis understanding and diagnostic and management strategies.
1 citations
,
May 2023 in “Research journal of pharmacognosy and phytochemistry” This article discusses the growing preference for organic and herbal cosmetics for hair care, attributing this trend to reduced side effects compared to their synthetic counterparts, and highlights ingredients like fenugreek, flaxseed, and ginger for their potential benefits in preventing hair issues and promoting growth.
1 citations
,
March 2023 in “European Journal of Human Genetics” This retrospective study observed that patients with vascular EDS on long-term angiotensin II receptor blockers or beta-blockers experienced fewer vascular events compared to those without cardiac medication under similar lifestyle and emergency care advice.