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    Glossary Premature Aging

    accelerated appearance of aging signs earlier than typical

    Premature aging, also known as early aging, refers to the accelerated appearance of signs of aging, such as wrinkles, gray hair, and loss of skin elasticity, occurring earlier than the typical age range. This can be caused by various factors including genetics, environmental stressors like UV radiation, lifestyle choices such as smoking and poor diet, and underlying medical conditions. Understanding the mechanisms behind premature aging can help in developing targeted interventions to slow down or mitigate its effects.

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    1. Premature aging syndromes: From patients to mechanism Journal of dermatological science · 2019 · 29 citations
    2. Premature aging and cancer development in transgenic mice lacking functional CYLD Aging · 2019 · 16 citations
    3. Loss of Stem Cells Correlates with Premature Aging in Animal Study, Penn Researchers Find Cancer biology & therapy · 2007
    4. Hutchinson-Gilford Progeria Syndrome: Premature Aging 2026
    5. 559 Induction of tissue-specific premature stem cell aging promotes senescence-like phenotypes in remote multiple organs Journal of Investigative Dermatology · 2022
    6. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Autophagy · 2021 · 6 citations
    7. Elastogenesis Stimulation by Minoxidil or Nebivolol Reduces Premature Aging of the Aortic Wall in Diabetic Mice 2024
    8. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2022
    9. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2021
    10. DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho−/− mice Cardiovascular diabetology · 2017 · 20 citations
    11. Cutaneous features of myotonic dystrophy types 1 and 2: Implication of premature aging and vitamin D homeostasis Neuromuscular Disorders · 2016 · 18 citations
    12. Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice GeroScience · 2025 · 4 citations
    13. Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage ˜The œFASEB journal · 2006 · 210 citations
    14. Do Changes in Chromosomes Cause Aging? Cell · 1996 · 50 citations
    15. Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage PLOS ONE · 2013 · 30 citations
    16. ST Premature Graying Hair in Seven Years Old Children Jurnal Biomedika dan Kesehatan · 2024
    17. Oxidative stress in ageing of hair International Journal of Trichology · 2009 · 126 citations
    18. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction Journal of Dermatological Science · 2017 · 35 citations
    19. Androgenic Alopecia and Stress-Induced Premature Senescence by Cumulative Ultraviolet Light Exposure Exogenous Dermatology · 2002 · 27 citations
    20. The circadian molecular clock creates epidermal stem cell heterogeneity Nature · 2011 · 293 citations
    21. Smoking and the skin International Journal of Dermatology · 2012 · 114 citations
    22. Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse PLoS ONE · 2012 · 42 citations
    23. Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation Stem cells · 2017 · 13 citations
    24. Dermatologic Signs and Symptoms of Substance Abuse Journal of clinical & experimental dermatology research · 2016 · 11 citations
    25. Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities Plants · 2022 · 7 citations
    26. Werner's syndrome: incidental finding during pregnancy BMJ case reports · 2013 · 1 citations
    27. GRAY HAIR OR BALD HEADS JAMA · 1942 · 1 citations
    28. Formulasi Sampo Padat dari Ekstrak Etanol Daun Tin (Ficus carica L.) sebagai Antioksidan Bandung Conference Series Pharmacy · 2025
    29. Cosmetic Benefits of Shirodhara Treatment: A Comprehensive Review of Its Impact on Scalp, Hair and Skin Health International Journal Of Ayurvedic And Herbal Medicine · 2024
    30. Cisd2 deficiency impairs neutrophil function by regulating calcium homeostasis via Calnexin and SERCA BMB Reports · 2024