November 2023 in “International Journal of Cosmetic Science” This study found that a wheat polar lipid complex supplement significantly reduced hair loss and improved hair growth and volume in women experiencing acute hair shedding, including postmenopausal women.
November 2023 in “Indian Journal of Dermatology” This study from North-East India analyzed 21 cases of frontal fibrosing alopecia, noting a high prevalence in post-menopausal women and distinct histological features such as perifollicular lymphocytic infiltrate and hydropic degeneration.
August 2023 in “Authorea (Authorea)” This article highlights that tinea capitis, a fungal scalp infection primarily seen in children, is often misdiagnosed in adults, especially postmenopausal women and immunocompromised individuals, leading to unnecessary treatments and potential permanent hair loss if not correctly identified and treated.
In this retrospective study, researchers at a Spanish hospital found that the severity of frontal fibrosing alopecia, primarily affecting postmenopausal women, was correlated with the duration of the disease, though inflammatory signs were not linked with its progression.
This review clarifies that non-anaemic iron deficiency in non-pregnant premenopausal women often arises from menstrual iron losses and can cause symptoms like hair loss, while in post-menopausal women and adult men, iron deficiency anaemia frequently indicates chronic intestinal bleeding.
In this study, researchers found that an injectable solution of low-molecular-weight hyaluronic acid and amino acids significantly improved skin rejuvenation and elasticity in the labia majora of post-menopausal women over 12 weeks, with a reported 25% or greater aesthetic improvement and high patient satisfaction.
5 citations
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November 2013 in “Case reports in dermatology” This case report details a 57-year-old woman with frontal fibrosing alopecia who developed hyperpigmentation after treatment with dutasteride and pimecrolimus, highlighting no previously reported hyperpigmentation association with this combination.
33 citations
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January 2010 in “Case reports in dermatology” This article presents a case study of a 50-year-old woman with frontal fibrosing alopecia and discusses the role of dermoscopy in differentiating it from other types of alopecia, reporting no new clinical results.
29 citations
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July 2010 in “Journal of Cutaneous Medicine and Surgery” This study reported no significant improvement in patients with frontal fibrosing alopecia treated with various therapeutic agents, highlighting the need for more evidence-based treatments, especially in those with active disease.
5 citations
,
October 2013 in “Endocrine” This case report describes three instances where occult ovarian Leydig cell tumors were suspected based on severe hyperandrogenism symptoms, despite negative imaging findings, highlighting that elevated testosterone levels are a crucial diagnostic marker.
14 citations
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January 2018 in “Skin Appendage Disorders” This case report suggests that identifying hyperpigmentation on the upper eyelid with specific dermoscopy patterns could help diagnose facial lichen planus pigmentosus without needing a facial biopsy.
1 citations
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April 2016 in “The American Journal of the Medical Sciences” This article discusses the characteristics of lichen planus pigmentosus and frontal fibrosing alopecia but reports no new clinical findings; the authors review existing knowledge.
January 2013 in “Revista Clínica Española” This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.
3 citations
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May 2011 in “Journal of Obstetrics and Gynaecology” This review discusses the characteristics of benign biphasic ovarian neoplasms called adenofibromas and reports no new clinical findings.
November 2025 in “Journal of Investigative Dermatology” Estetrol may help prevent hair loss and support hair growth in women.
August 2025 in “Cosmetics” This review discusses the possible link between cosmeceuticals and frontal fibrosing alopecia but reports no conclusive findings; the authors stress further research on environmental triggers is needed.
This manuscript reviews the multifaceted causes of female hair loss, including hormonal imbalances and nutrient deficiencies, and suggests that non-pharmaceutical options like saw palmetto and curcumin show promise in enhancing hair density, though further studies are needed to confirm their effectiveness and safety.
January 2025 in “Indian Journal of Dermatology” This review discusses the various factors implicated in the etiology of frontal fibrosing alopecia and notes the need for effective treatments, reporting no new clinical findings.
166 citations
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April 2012 in “Journal of The American Academy of Dermatology” This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.
159 citations
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August 2010 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, hydroxychloroquine significantly reduced signs and symptoms of frontal fibrosing alopecia after 6 months of treatment, with maximal benefits observed within the first 6 months.
102 citations
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April 2014 in “International Journal of Dermatology” This study found that early intervention and treatment with intralesional triamcinolone acetonide may stabilize hairline recession in patients with frontal fibrosing alopecia, although further research is needed for definitive treatment guidelines.
25 citations
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December 2017 in “Facial Plastic Surgery” This study observed that combining high-potency steroids with pimecrolimus might effectively stabilize hairline recession in frontal fibrosing alopecia patients.
21 citations
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December 2012 in “Maturitas” This study observed significant inter- and intra-individual variability in serum testosterone levels among women treated with subcutaneous testosterone implants, suggesting that therapy should be guided by clinical response rather than single serum measurements.
6 citations
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January 2019 in “Medical Hypotheses” This hypothesis article explores frontal fibrosing alopecia as a potential autoimmune condition and calls for future research to investigate this possibility, but reports no new clinical results.
4 citations
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April 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review highlights available treatments for frontal fibrosing alopecia, noting that 5-alpha reductase inhibitors, intralesional steroids, and hydroxychloroquine currently have the most evidence supporting their use, while other treatments show variable results and require further study.
2 citations
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July 2022 in “Frontiers in Medicine” This review discusses the current understanding of frontal fibrosing alopecia's pathogenesis, highlighting genetic susceptibility, immune response involvement, and possible links to steroid hormones, but reports no new clinical results.
1 citations
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May 2025 in “Maturitas” This article highlights that hormonal changes during menopause can significantly affect hair health, leading to decreased hair density, altered texture, and increased hair disorders, which may subsequently impact emotional well-being in women.
1 citations
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September 2021 in “CRC Press eBooks” This chapter reviews trichoscopic-pathologic correlations in Frontal Fibrosing Alopecia and reports no new clinical results; the authors discuss genetics, clinical patterns, and unusual variants associated with this condition.
April 2019 in “Journal of the Endocrine Society” This study reported that testosterone levels over 150 ng/dL combined with lack of testosterone suppression during a low-dose dexamethasone suppression test may indicate androgen-producing tumors, though this wasn't consistent across all cases.
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