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5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Treat pattern hair loss with finasteride and topical minoxidil.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.

A herbal extract may help treat certain types of hair loss by reducing a specific gene's activity.

Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Many research paper titles in dermatology journals lack scientific precision.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The document is a detailed medical reference on skin and genetic disorders.

Nanotechnology shows promise for better drug delivery and cancer treatment.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

Muscles can make their own androgens, which may help muscle growth.

Extracts from Alnus sibirica and oregonin may help with hair growth and prevent hair loss.

CuSi nanowires with NIR photothermal properties could effectively treat infected wounds and promote healing.

Chitosan-decorated nanoparticles can improve skin delivery and reduce side effects of finasteride.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.