January 2023 in “Journal of Ravishankar University” Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.
January 2023 in “International Journal of Molecular Sciences” Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
December 2022 in “Frontiers in Pharmacology” Tianma Gouteng decoction may help prevent hair loss and promote hair growth.
December 2022 in “Cosmetics” The food supplement improved hair growth and strength in people with a certain type of hair loss and had no major side effects.
September 2022 in “Frontiers in Bioengineering and Biotechnology” Taxifolin from Rhododendron mucronulatum may help prevent hair loss and promote hair growth.
May 2022 in “International Journal of Health Sciences (IJHS)” Hibiscus Rosa Sinensis Linn is a tropical plant used for various medicinal purposes due to its many beneficial properties and components.
November 2020 in “IntechOpen eBooks” Not getting enough minerals can lead to health problems and shorter lifespans.
January 2020 in “Journal of dermatology research and therapy” Most over-the-counter hair loss treatments lack strong evidence of effectiveness but cost nearly as much as the proven treatment, minoxidil.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
July 2018 in “Madridge journal of dermatology & research” Cactus-enriched hair oil effectively reduces hair fall and promotes hair growth with no major side effects.
January 2017 in “Archives of Aesthetic Plastic Surgery” Hair care products with placental growth factor can improve hair thickness and density in postpartum hair loss.
January 2017 in “Journal of Dermatology and Venereology” Naringenin and Hesperetin may help hair grow and protect hair cells from damage.
January 2023 in “Applied sciences” Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.
February 2023 in “PLOS ONE” Caizhixuan hair tonic helps treat hair loss by promoting hair growth and improving hair follicles.
260 citations,
July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
85 citations,
March 2012 in “Revista Brasileira de Farmacognosia” The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.
75 citations,
January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
72 citations,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
58 citations,
April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
46 citations,
September 2011 in “Journal of Endocrinology” Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
38 citations,
October 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.
33 citations,
December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
21 citations,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
20 citations,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
15 citations,
May 2004 in “Facial Plastic Surgery Clinics of North America” Treat pattern hair loss with finasteride and topical minoxidil.
14 citations,
April 2021 in “Biology” Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.