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    Did you mean Tissue Plasminogen Activator?
    Glossary Tissue Plasminogen Activator

    protein that dissolves blood clots by activating plasminogen

    Tissue Plasminogen Activator (TPA) is a protein involved in the breakdown of blood clots. It converts plasminogen, an inactive protein in the blood, into plasmin, an enzyme that dissolves clots. TPA is often used in medical treatments to quickly dissolve clots in patients experiencing heart attacks or strokes.

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    Research 30 of 391

    1. Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation 1998 · 42 citations
    2. Role of plasminogen activator inhibitor type 1 (PAI-1) in PCOS patient International journal of reproduction, contraception, obstetrics and gynecology · 2017 · 3 citations
    3. Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women BMC women's health · 2023 · 2 citations
    4. Urokinase plasminogen activator (uPA) is a positive regulator of outer root sheath keratinocyte proliferation Cell Biology International · 2004 · 2 citations
    5. Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity Frontiers in molecular biosciences · 2022 · 3 citations
    6. trans-3,4'-Dimethyl-3-hydroxyflavanone, a Hair Growth Enhancing Active Component, Decreases Active Transforming Growth Factor .BETA.2 (TGF-.BETA.2) through Control of Urokinase-Type Plasminogen Activator (uPA) on the Surface of Keratinocytes Biological and Pharmaceutical Bulletin · 2008 · 10 citations
    7. Anaphylactic Shock Due to Intravenous Amiodarone; Delusional Parasitosis Associated with Donepezil; Connubial Androgenetic Alopecia; Ciprofloxacin-Induced Torsade de Pointes; Postvaccination Miller Fisher Syndrome; Life-Threatening Anaphylactoid Shock Caused by Recombinant Tissue Plasminogen Activator; Thiazide-Induced Hyponatremia Hospital Pharmacy · 2012
    8. Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome Gynecological Endocrinology · 2009 · 29 citations
    9. Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells Experimental Dermatology · 2012 · 6 citations
    10. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    11. Wound healing in development Birth Defects Research · 2012 · 29 citations
    12. Urokinase is a Positive Regulator of Epidermal Proliferation In Vivo Journal of Investigative Dermatology · 1999 · 28 citations
    13. Evaluation of cardiac risk marker levels in obese and non-obese patients with polycystic ovaries Gynecological Endocrinology · 2016 · 21 citations
    14. Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration MOJ proteomics & bioinformatics · 2015
    15. 644 Tumor cell adhesion as a risk factor for SLN metastasis and predictor of disease recurrence in primary cutaneous melanoma Journal of Investigative Dermatology · 2016
    16. Ku80 as a Novel Receptor for Thymosin β4 That Mediates Its Intracellular Activity Different from G-actin Sequestering Journal of Biological Chemistry · 2007 · 37 citations
    17. Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit 2013 · 9 citations
    18. Protease-Activated Receptor-1 (Thrombin Receptor) Is Expressed in Mesenchymal Portions of Human Hair Follicle Journal of Investigative Dermatology · 2003 · 7 citations
    19. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017 · 77 citations
    20. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    21. Current Concepts and Translational Uses of Platelet Rich Plasma Biotechnology InTech eBooks · 2015 · 12 citations
    22. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    23. The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration 2010
    24. Mechanisms of Puerariae Lobatae Radix in regulating sebaceous gland secretion: insights from network pharmacology and experimental validation Frontiers in Pharmacology · 2024 · 3 citations
    25. JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing Scientific Reports · 2017 · 54 citations
    26. Forsythiaside A protects against focal cerebral ischemic injury by mediating the activation of the Nrf2 and endoplasmic reticulum stress pathways Molecular Medicine Reports · 2019 · 12 citations
    27. Regulation of Involucrin Gene Expression Journal of Investigative Dermatology · 2004 · 138 citations
    28. MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy Stem Cell Research & Therapy · 2021 · 25 citations
    29. Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier European Journal of Medicinal Chemistry · 2024 · 4 citations
    30. Fibroblast Growth Factor-7 and Hair Biology: Bridging Basic Science and Therapeutic Applications Current Issues in Molecular Biology · 2026