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This review discusses the evolution of platelet concentrates in regenerative medicine, highlighting a proposed function-driven classification that distinguishes three generations of PCs by biological activity rather than development order, with third-generation exosome-based therapies showing superior therapeutic efficacy over earlier formulations.

This study found that follicular unit extraction megasession resulted in high patient satisfaction without infections for treating severe androgenetic alopecia, offering a promising one-stage option compared to multi-stage hair transplants.

This study found that while PRP or nanofat injections improved scarred tissue texture in secondary cicatricial alopecia, they did not significantly enhance hair restoration outcomes compared to hair transplantation alone.

This article reviews the use of autologous platelet-rich plasma (PRP) in hair restoration, discussing its potential benefits for follicle health and regeneration, but it reports no new clinical findings.

This systematic review reports that regenerative medicine therapies, such as conditioned media, platelet-rich fibrin, and stem cells, show promising efficacy and safety in treating androgenetic alopecia, though heterogeneity in study protocols and limited long-term data emphasize the need for further research to optimize these strategies.

This study reported that participants applying topical human platelet exosome extract serum experienced significant improvements in hair volume, density, scalp coverage, and overall hair health compared to a placebo, and no adverse effects were observed.

This study found that using platelet-rich plasma alongside minoxidil and finasteride/spironolactone during hair transplant surgery for androgenetic alopecia improved follicle survival, hair growth rates, and hair strength.

This source notes that minoxidil and finasteride are the most supported treatments for androgenetic alopecia, with combination treatments like PRP showing promise, while the role of saw palmetto remains unclear.

This study suggests that minoxidil and finasteride are the most supported treatments for androgenetic alopecia, with promising combination therapies like PRP, while saw palmetto's effectiveness remains unclear.

This systematic review suggests that intraoperative corticosteroids can reduce postoperative edema in FUE hair transplantation donor areas, but highlights a need for more mechanistic studies to improve understanding of tissue regeneration.

This study concluded that preparing scars with either platelet-rich plasma or CO₂ laser significantly improved outcomes in hair transplantation for patients with cicatricial alopecia.

This study found that using PRP with the FUE method of hair restoration led to better graft survival, aesthetic outcomes, and patient satisfaction compared to not using PRP.

In this study, PRP after FUE increased hair density and length in men with androgenetic alopecia, with no scalp redness reported beyond the first month.

This review discusses the potential of extracellular vesicles from various sources for skin rejuvenation and cosmetic use, noting promising results, especially with mesenchymal stem cell-derived vesicles, but reports no new clinical results.

This study concluded that using platelet-rich plasma in follicular unit extraction for post burn alopecia is beneficial, offering fewer hazards and complications, and a shorter recovery time compared to other hair restoration procedures.

This review suggests that platelet-rich plasma therapy shows promise for androgenetic alopecia and may be effective for some alopecia areata and cicatricial alopecia cases, but more robust trials are needed.

This book chapter reviews the subclasses and applications of platelet-rich plasma in tissue engineering and highlights the challenges in clinical translation without reporting new clinical results.

This chapter reviews the clinical evidence of adding platelet-rich plasma to lipofilling for tissue regeneration, with suggestions of benefits in skin rejuvenation and wound healing, but lacks well-designed trials.

This study found that injections of extracellular vesicles derived from mesenchymal stem cells improved hair growth in over 50% of female and nearly 80% of male patients after six months.

This article discusses the potential use of human hair follicular stem cells combined with platelet-rich plasma for androgenetic alopecia, focusing on the regenerative processes involved, but reports no new clinical results.

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

This case report demonstrated that long-hair follicular unit extraction may effectively reconstruct the mustache area following surgical scarring, with high patient satisfaction and no complications observed.

This study found that two finasteride preparations were bioequivalent in human volunteers when tested using a new HPLC method for pharmacokinetics.

This case report describes an increase in crown hair coverage using body hair transplantation from the chest and suprapubic regions, suggesting these as viable donor sites but emphasizing the need for standardized patient selection and follow-up.

This study developed and validated a sensitive and rapid method to simultaneously measure alfuzosin and dutasteride in human plasma, enabling high-throughput analysis for pharmacokinetic and bioequivalence studies.

In this case report, a 36-year-old woman with systemic lupus erythematosus and alopecia related to discoid lupus erythematosus showed hair regrowth following treatment with concentrated growth factor, suggesting its potential as a cosmetic therapy for DLE.

This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

This review discusses advancements in regenerative medicine for hair loss treatments, highlighting stem cell techniques for rejuvenating or creating hair follicles, but provides no new clinical results.

In this systematic review, the authors reported that both FUE and FUT hair transplant techniques induce oxidative stress and inflammation, impacting graft survival, but interventions like PRGF, CO2 laser, and dermal microtissues can enhance healing, reduce inflammation, and improve follicular survival.