12 citations
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October 2017 in “Journal of Cosmetic Dermatology” This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.
39 citations
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June 2013 in “Journal of Cosmetic Dermatology” This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.
39 citations
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January 2016 in “Journal of Cutaneous and Aesthetic Surgery” This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.
28 citations
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September 2020 in “International Journal of Molecular Sciences” This study concluded that leucocyte-rich PRP has a continuous stimulatory effect on human fibroblast cells, enhancing their proliferation, migration, and impacting gene expression of the extracellular matrix and adhesion molecules.
4 citations
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January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
3 citations
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February 2023 in “International Journal of Molecular Sciences” This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
March 2026 in “Journal of Maxillofacial and Oral Surgery” This study found that using intraoperative platelet-rich plasma in follicular unit extraction hair transplantation significantly improved graft survival, accelerated hair regrowth, and increased patient satisfaction compared to the procedure without PRP.
October 2025 in “Journal of Pharmacy And Bioallied Sciences” This study concluded that platelet-rich plasma significantly improves hair density and patient satisfaction for individuals undergoing follicular unit extraction for androgenetic alopecia compared to those receiving the surgery alone.
January 2025 in “The World Journal of Men s Health” In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.
December 2024 in “Journal of Cosmetic Dermatology” This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.
September 2024 in “Zagazig University Medical Journal” This study concluded that incorporating platelet-rich plasma into follicular unit extraction improved scar tissue texture and quality but did not significantly enhance hair restoration results in non-androgenic alopecia.
May 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that combining hair transplantation with PRP therapy resulted in better quality and increased growth of new hair, while also speeding up skin healing and reducing hair loss post-transplant.
July 2022 in “Journal of Cosmetic Dermatology” This study found that follicular unit extraction, with or without platelet rich plasma, is effective for hair restoration in cicatricial alopecia, though PRP does not significantly impact graft survival rates.
June 2022 in “Ain Shams medical journal” This study found that incorporating platelet-rich plasma in hair transplant procedures for cicatricial alopecia improved patient satisfaction and hair growth outcomes compared to procedures without it.
June 2020 in “Al-Azhar International Medical Journal (Print)” This study found that platelet-rich plasma therapy after follicular unit extraction hair transplantation improves recovery time and hair density in cicatricial alopecia patients, but not in those with androgenic alopecia.
March 2021 in “Zagazig university medical journal” This study found that Platelet Rich Plasma significantly enhances hair density and quality when used with Follicular Unit Extraction in treating androgenic alopecia.
7 citations
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September 2014 in “Mass spectrometry letters” This study reported that a liquid-liquid extraction method using methyl tert-butyl ether and methylene chloride was most effective for extracting dutasteride and its internal standard from rat plasma.
1 citations
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August 2023 in “International Journal of Molecular Sciences” This review compiles evidence from 20 relevant studies and suggests that platelet-rich plasma-derived extracellular vesicles represent a promising therapeutic option in regenerative medicine, although the authors emphasize the need for standardized protocols due to inconsistencies across studies.
August 2023 in “Journal of Chromatographic Science” This study developed a reliable UHPLC-MS/MS method to measure flavonoids from Pinus massoniana needles in rat plasma for pharmacokinetics, aiding further research on their potential use in external preparations to prevent hair loss.
May 2022 in “International Journal of Clinical Trials” This study concluded that platelet rich fibrin (PRF) may enhance healing and functional recovery compared to platelet rich plasma (PRP) during immediate post-extractive dental implant procedures.
2 citations
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February 2023 in “Shiraz E-Medical Journal” In this study, low-level laser therapy significantly improved the mechanical strength of bone at tooth extraction sites in rats, while neither platelet-rich plasma alone nor combined with laser affected mechanical strength or calcium content.
15 citations
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June 2018 in “Journal of Chromatographic Science” This study successfully developed a method to measure four flavonoids from Platycladus orientalis leaves in rat plasma, which was used in a pharmacokinetic study on healthy rats.
823 citations
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February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
5 citations
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April 1946 in “PubMed” This study found that a diet with purified casein and sulfasuxidine resulted in poor growth and anemia in a pig, which improved after treatment with a liver extract.
88 citations
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December 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that interfollicular injection of autologous CD34+ cell-containing PRP preparation improved hair count and thickness in patients with pattern hair loss, with better results than placental extract treatment.
May 2026 in “Malaysian Journal of Medicine and Health Sciences” This study found that in a testosterone-induced androgenetic alopecia mouse model, the combination of PRP-derived small extracellular vesicles and 5% minoxidil significantly improved hair follicle density and the anagen-to-telogen ratio compared to minoxidil alone, suggesting a synergistic effect that enhances hair growth.
This study proposes that neutralizing antibodies and exosomes in convalescent plasma may interfere with early immune responses, potentially explaining limited success of this therapy in active COVID-19 infections.
January 2022 in “Springer eBooks” This study reported that platelet-rich plasma therapy showed a positive response in improving hair density and thickness among patients with androgenic alopecia.
26 citations
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January 2016 in “Journal of cutaneous and aesthetic surgery” Hair transplant combining scalp and beard hair with PRP was successful for scarring alopecia.
12 citations
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June 2018 in “Journal of Cosmetic Dermatology” This review outlines recent research on platelet-rich plasma, alone or combined with other therapies, for managing hair loss disorders, and discusses future prospects without reporting new clinical findings.