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Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Finasteride effectively blocks enzyme causing male pattern baldness.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Finasteride effectively treats baldness but may cause sexual side effects.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

Finasteride may cause slight depression and anxiety.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.