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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

A male with aromatase deficiency improved bone health with estradiol treatment.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.