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This review discusses the use of human and animal-derived placental and umbilical extracts in cosmetics, highlighting insufficient data to establish their safety and recommending they should not have metabolic or endocrine activity.

This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.

This study suggests that a purified sphingolipid fraction can activate melanocyte stem cells via p38 signalling, potentially offering a non-UV-based treatment for vitiligo, though additional validation is needed.

This study found that a solution containing 0.5% Camellia japonica placenta extract increased scalp moisture and reduced sebum content, dead keratin, and erythema in adult females, suggesting potential as a scalp treatment.

This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.

This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.

This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.

This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by modulating key signaling pathways, suggesting a novel therapeutic approach for degenerative diseases.

This paper discusses X-linked ichthyosis and its genetic causes, focusing on biochemical pathways and their role in epidermal differentiation and barrier function, but it presents no new clinical findings.

This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.

This review outlines the biological effects of various placental extracts, noting their reported antioxidant, anti-inflammatory, and immunomodulatory activities, but highlights that the relationship between these effects and the extracts' specific contents remains unclear.

In this phase I/II clinical trial, placenta-derived mesenchymal stem cell exosome therapy significantly improved hair density and diameter, and reduced hair loss in patients with androgenetic alopecia, though further large-scale studies are needed to confirm these results and investigate the underlying molecular mechanisms.

This document extends previous recommendations by the National Lipid Association for managing dyslipidemia, focusing on lifestyle therapies, special patient groups, and strategies to enhance adherence and patient outcomes.

This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.

In this study, human placenta extract was observed to enhance the hair-growth-promoting effects of minoxidil and stimulate earlier and prolonged anagen phases in a mouse model.

This study identified key lipid differences between black and white hair in individuals with premature greying, highlighting vitamin D3 as a potential target for further research in understanding this condition.

This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.

This study found that human placental extract significantly improved melasma, chronic ulcers, and alopecia areata without major adverse effects, suggesting its effectiveness and safety for these conditions.

This review discusses the timing and management of dyslipidemia screening around pregnancy and emphasizes dietary, exercise, and glycemic interventions during pregnancy without reporting new clinical outcomes.

This review discusses the timing and management of dyslipidemia screening and intervention in pregnancy and highlights the need for lipid profile assessments each trimester; it reports no clinical results.

This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.

In this study, researchers observed that Malassezia species show different lipid metabolism and growth patterns depending on pH, with slightly acidic conditions promoting beneficial lipid bio-conversion for skin health, while neutral pH resulted in lower growth and lipid content, potentially negatively impacting the skin.

In this study, higher DHA/omega-6 fatty acid ratios were linked to increased social impairment in individuals with autism, alongside lower antioxidant enzyme levels and higher markers of lipid peroxidation.

This study found that a high percentage of pediatric sickle cell disease patients have parents from medium-high socioeconomic status, indicating that the educational background of parents did not influence the disease's prevalence.

The study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in HUVECs, with early pregnancy cells showing more significant effects than those from full-term pregnancy.

This study suggests that maternal hyperandrogenism and insulin resistance may induce ferroptosis in the gravid uterus and placenta in rats, but through distinct molecular mechanisms.

This study found that bioactive extracts from goat placenta, particularly when delivered via dissolving microneedles, enhanced fibroblast proliferation and skin regeneration without being toxic to skin cells, suggesting a promising dermal application for improving skin health.

This study found that porcine-placenta-extract-loaded nanoformulated serum improved skin hydration and promoted hair growth, as well as reduced intracellular ROS and inflammation without cytotoxicity in human subjects.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

This study found that a combination of low-dose flutamide and metformin therapy may reverse insulin resistance and reduce fat mass in nonobese adolescents with PCOS.