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Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Oral isotretinoin for severe acne can change hormone levels but does not significantly affect ovarian function.

Hair transplantation is the only permanent solution for female pattern hair loss and can greatly improve quality of life with careful planning.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.