January 2023 in “Health science reports” In this study, oral Pycnogenol® intake was reported to significantly increase hair density and improve scalp microcirculation in Han Chinese menopausal women over six months.
12 citations
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March 2019 in “Cosmetics” In this study, a combined regimen of an oral supplement with Pinus pinaster, Grape seed extract, vitamins, and minerals, plus high SPF sunscreen, significantly improved mild-to-moderate facial melasma in 30 women over 84 days, reducing pigmentation and enhancing cosmetic appearance with no reported adverse effects.
February 2026 in “Journal of Microbiology and Biotechnology” This study reported that abietic acid, derived from pine rosin, showed antimicrobial effects and reduced biofilm biomass in laboratory tests against microorganisms like Staphylococcus aureus and Candida albicans, suggesting potential further applications for skin infections.
January 2024 in “Figshare” This study suggests that a turpentine ointment may be an effective and safe treatment for acute folliculitis, as it showed improvements over placebo in lesion evolution, responder rate, and patient assessments.
1 citations
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October 2010 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the effectiveness of various plant extracts, including Vitis vinifera and Aesculus hippocastanum, in treating dermatological conditions like venous insufficiency and actinic keratoses but reports no new clinical results.
11 citations
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October 2016 in “Pediatric dermatology” This case study observed that three girls with alopecia experienced complete hair regrowth after avoiding balsam of Peru and related fragrances, suggesting contact allergy played a role in their hair loss.
August 2019 in “Pharmacoscript” This study found that a combination of pandanus and sansevieria leaf extracts at a 3:2 ratio showed improved hair growth activity compared to individual extracts and controls.
4 citations
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January 2023 in “Skin Pharmacology and Physiology” This study observed that an ointment containing pine turpentine oil, larch turpentine, and eucalyptus oil showed significant improvement over placebo in lesion evolution, responder rates, and patient assessments for treating acute folliculitis, while being well-tolerated across treatments.
January 2024 in “Figshare” This study concluded that an ointment containing pine turpentine oil, larch turpentine, and eucalyptus oil was an effective and safe treatment for folliculitis, showing improvement over placebo in lesion evolution, responder rate, and patient assessment.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses plant extracts for dermatological use, highlighting evidence that some can reduce edema in chronic venous insufficiency or help treat actinic keratoses, but it reports no new clinical results.
5 citations
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January 2007 in “Lincoln (University of Nebraska)” These investigations described in the study demonstrate how geochemical techniques can be applied to biological studies in Yellowstone, finding significant mercury accumulation in trout and grizzly bears which correlates with hydrothermal sources.
16 citations
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September 2022 in “International Journal of Molecular Sciences” This study reported that Juniperus sabina needle extract showed significant anti-butyrylcholinesterase activity, suggesting potential medicinal value due to high podophyllotoxin levels.
2 citations
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July 2019 in “International Journal of Neuroscience and Behavioral Science” This study found that ethanol extract of Thevetia peruviana bark demonstrated significant antinociceptive activity in mice, suggesting potential for developing new analgesic drugs.
January 2026 in “Dermatologic Therapy” This study found that Pinus massoniana needles extract may promote hair regrowth in a mouse model of androgenetic alopecia, potentially by reducing oxidative stress and affecting immune, metabolic, and apoptosis-related pathways.
53 citations
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July 2021 in “International Journal of Molecular Sciences” This study found that extracts from Geranium pyrenaicum show promising antioxidant, enzyme inhibitory, and antiviral activities, particularly the methanolic extract's antiviral activity against HSV-1.
12 citations
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May 2023 in “Molecules” This study identified seven potential enzyme inhibitors from a Polygonum cuspidatum extract using ultrafiltration combined with high-performance liquid chromatography. These compounds showed inhibitory activity against tyrosinase, α-glucosidase, and xanthine oxidase, with most discovered in this extract for the first time.
In this study, the ethanol extract of Tridax procumbens leaves exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria, with specific active compounds identified through GC-MS analysis that may contribute to its therapeutic potential.
2 citations
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February 2021 in “IOP Conference Series Earth and Environmental Science” This study identified that Mangkokan leaf extracts contain active compounds such as alkaloids, flavonoids, steroids, tannins, phenols, and saponins, using different solvents and FTIR analysis.
44 citations
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January 2007 in “Biological & pharmaceutical bulletin” This study found that Piper nigrum leaf extract showed in vivo anti-androgenic activity and potent 5α-reductase inhibitory effects, with piperine and (−)-cubebin identified as active components.
July 2017 in “Journal of Young Pharmacists” In this study, the ethyl acetate fraction of Nothopanax scutellarium leaves showed a mild irritation effect but promoted hair growth and increased hair diameter in rabbits.
1 citations
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August 2024 in “Polymers” This study observed that dissolving microneedles made from PVP-K90 and HPMC E50, incorporating Oryza sativa L. extract complex, showed enhanced transfollicular skin penetration and maintained safety for keratinocytes, with the P25H5 formulation demonstrating faster dissolution and greater effectiveness.
1 citations
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September 2025 in “Molecules” This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.
December 2025 in “International Journal of Molecular Sciences” This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.
61 citations
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September 2010 in “Fitoterapia” This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.
April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, Platycladus orientalis leaf extract loaded into hyaluronic acid microneedles was found to promote hair follicle growth by enhancing the environment for hair cell proliferation and activating repair pathways, suggesting potential as a treatment for androgenic alopecia.
December 2023 in “Natural product research” This study found that compound 4 from Urtica triangularis subsp. pinnatifida exhibited stronger anti-BPH activity against BPH-1 cells with an IC50 of 79.75 μM compared to finasteride's IC50 of 91.8 μM, while compounds 1, 2, and 5 showed moderate activity.
3 citations
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July 2015 in “International journal of pharmacology” In this study, Natural Plant Extracts (NPE) promoted hair growth in mice by stimulating anagen growth and upregulating relevant gene expression, compared to controls with saline.
6 citations
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October 2023 in “Pharmaceuticals” This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
January 2026 in “Chemistry & Biodiversity” This study found that the chemical composition and biological activity of Platycladus orientalis fruit extracts varied with the extraction method, revealing potent antioxidant and enzyme inhibitory properties, particularly in the n-hexane extract, which suggests potential applications for managing dysregulated enzyme conditions.
19 citations
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January 2009 in “Journal of Young Pharmacists” This study found that the alcoholic extract of Eclipta alba exhibited dose-dependent antianaphylactic effects in animal models, possibly due to membrane stabilization and reduced histamine release.