6 citations
,
March 2010 in “Journal of plastic, reconstructive & aesthetic surgery” This article reviews the evolution of syndactyly repair techniques, highlighting a shift towards graftless approaches to avoid complications associated with skin grafts, but reports no new clinical outcomes.
4 citations
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May 2023 in “Pigment Cell & Melanoma Research” In this study, researchers found that deleting the Bmi1 gene in murine melanocytes caused premature hair greying and loss of melanocyte lineage cells, highlighting BMI1's role in protecting melanocyte stem cells from stress and oxidative damage.
3 citations
,
January 2019 in “Journal of Dermatology” This letter to the editor discusses the natural course of epidermolysis bullosa simplex with mottled pigmentation in a Japanese family but does not present new clinical results.
3 citations
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January 2019 in “Advances in stem cells and their niches” This review discusses the role of dermal papilla cells in hair follicle morphogenesis and regeneration and reports no new results; the authors emphasize the importance of these cells in hair growth and pigmentation regulation.
2 citations
,
May 2023 in “Photobiomodulation, photomedicine, and laser surgery” This editorial reviews how photobiomodulation therapy might effectively treat both hyperpigmentation and depigmentation skin disorders, but reports no new clinical results.
2 citations
,
January 2002 This study investigated the pigments and cells causing discoloration in stasis dermatitis but did not clarify the role of melanin or melanocytes in this condition.
1 citations
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August 2018 in “Journal of The American Academy of Dermatology” Patients with melanoma who saw dermatologists and were from higher-income areas were more likely to have follow-up visits, which was linked to lower mortality.
1 citations
,
June 2011 in “InTech eBooks” This review discusses the role of melanocytes in skin pigmentation and UV protection, explaining their interactions with keratinocytes and highlighting their involvement in processes like melanin transfer and melanoma development, but reports no new results.
1 citations
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April 2008 in “Pigment Cell & Melanoma Research” This study suggests that Foxn1 expression in keratinocytes influences pigmentation in mice, highlighting differences in the molecular mechanisms between mouse and human pigmentation processes.
August 2026 in “Journal of Genome Biotechnology and Genetics” This review found that while forensic DNA phenotyping and health applications for pigmentation genetics show potential, factors like phenotype definition and population diversity present challenges to accurate genotype-to-appearance predictions.
July 2025 in “Advanced Science” In this study, researchers discovered two new signaling pathways that regulate how melanocytes establish pigment patterns in reconstituted hair-bearing skin, offering insights that could inform strategies to prevent hair greying.
February 2025 in “The Open Dermatology Journal” In this study conducted at Afzalipour Hospital in Iran, researchers found a significant prevalence of alopecia, particularly resembling telogen effluvium, among COVID-19-recovered patients, with hair loss being more common in females and correlating with arterial oxygen saturation levels.
August 2024 in “Journal of the American Academy of Dermatology” Nail color change might be an early sign of skin pigmentation from minocycline.
March 2024 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān/Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān./Zahedan journal of researches in medical sciences” This case study describes the successful treatment of facial pigmentation using microneedling combined with platelet-rich plasma, suggesting high effectiveness with minimal side effects in this application.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that neonatal Regulatory T cells are crucial for maintaining PPARγ signaling in hair follicles, which supports melanocyte stem cell function and skin pigmentation during early postnatal development.
November 2021 in “Natural product research” This study observed that the aqueous extract of roasted Alocasia macrorrhizos tubers led to hair follicle repigmentation and reduced epidermal thickness in a murine model of Vitiligo.
October 2019 in “International journal of research in dermatology” This case report describes two instances of hyper-pigmentation induced by prolonged misuse of Betnovate cream, where cessation and appropriate treatment led to significant improvement within 15 days.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrates that extracellular ATP induced by UV radiation promotes melanin production in human melanocytes, suggesting ATP-induced purinergic signaling may influence skin pigmentation.
September 2012 in “British Small Animal Veterinary Association eBooks” This article discusses pigmentation disorders in veterinary dermatology, focusing on the role of melanogenic pigmentation, and reports no new research results.
January 2007 in “Journal of the American Academy of Dermatology” A 73-year-old man's grey-white hair turned dark brown after eczema treatment.
This study suggests that holes found in mature hair fibers may be linked to daily hair care actions and the removal of extractable substances.
81 citations
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October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that silencing clock genes BMAL1 or PER1 in human hair follicles increased melanin content and melanocyte activity, suggesting these genes influence pigmentation.
32 citations
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May 2023 in “Preprints.org” This review discusses the types, causes, and treatments for skin pigmentation disorders, examining clinically tested options including 25 plants, four marine species, and 17 medications.
29 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, silencing P-cadherin in human scalp hair follicles reduced melanogenesis and associated protein expression, suggesting P-cadherin is crucial for normal hair pigmentation via GSK3β-mediated Wnt signaling.
15 citations
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January 2017 in “Pigment International” This article reviews the pathogenesis and treatment approaches for premature graying of hair, noting the unsatisfactory options currently available, and reports no new clinical findings.
6 citations
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August 2019 in “PLOS ONE” The researchers reported that Gambogic Amide may prevent hair greying and promote hair growth by maintaining follicle pigmentation in vitro through activation and migration of melanocytes.
3 citations
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October 2019 in “Pharmaceutics” This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.
2 citations
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November 2024 in “JAAD reviews.” This review reported that certain systemic drugs, including antiepileptics and anticancer drugs, can lead to changes in hair pigmentation, such as hypopigmentation or hyperpigmentation, with varied prevalence and clinical characteristics.
2 citations
,
January 2002 in “Clinics in Dermatology” This review details the characteristics, associations, and differential diagnoses of vitiligo and reports no new clinical findings.
1 citations
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September 2024 in “Journal of Oncology Pharmacy Practice” In this report, a 77-year-old woman treated for essential thrombocytosis with low-dose hydroxyurea experienced an unexpected change in hair color from gray to dark brown after 20 weeks, highlighting a potential aesthetic side effect of the drug, in addition to therapeutic effects.