January 2012 in “RWTH Publications (RWTH Aachen)” This study found that patient-derived HGF significantly accelerates wound healing in diabetic mice, particularly improving skin structure and flexibility, and rHGF plays a key role in boosting hair growth.
10 citations
,
April 2019 in “Environmental Science and Pollution Research” In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.
1 citations
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February 2022 in “Open Access Macedonian Journal of Medical Sciences” This study found that lower zinc serum levels may contribute to premature hair graying in college students at Universitas Sumatera Utara.
August 2025 in “Dermatology Reports” This study suggests that rosemary oil use may reduce the likelihood of premature hair greying among users in Saudi Arabia, though further research is needed to validate these findings.
April 2017 in “Journal of Investigative Dermatology” In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.
277 citations
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July 2002 in “Molecular Endocrinology” In this study, homozygous VDR null mutant mice exhibited nonfunctional vitamin D receptors, leading to growth abnormalities and revealing the limited physiological importance of vitamin D pathways outside the classical receptor.
114 citations
,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” This review discusses various skin side effects from chemotherapy, noting that they are mainly toxic rather than allergic and often include alopecia, which can cause significant distress to patients.
113 citations
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December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This study reports that overexpression of activin in transgenic mice enhances granulation tissue formation during wound healing, highlighting a novel role for activin in cutaneous repair processes.
43 citations
,
June 2012 in “Lasers in Medical Science” In a rat model of chemotherapy-induced alopecia, this study found that low-level laser treatment significantly accelerated hair regrowth without affecting the efficacy of chemotherapy.
24 citations
,
October 2017 in “Scientific reports” This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.
20 citations
,
September 2019 in “Journal of Cosmetic Dermatology” This study found that combining stromal vascular fraction with PRP injections significantly improved hair density and reduced hair loss more effectively than PRP alone in patients with androgenetic alopecia.
18 citations
,
January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.
16 citations
,
February 2019 in “Gene” This study describes two methods for isolating hair follicle stem cells from newborn Yangtze River Delta White Goats, highlighting differences in cell viability and marker protein expression between the methods.
15 citations
,
November 2022 in “Cell Death and Disease” In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.
14 citations
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November 2018 in “Journal of Cosmetic Dermatology” In this study, patients with androgenetic alopecia treated with platelet-rich plasma showed increased hair density and improved hair quality over six months, with no notable adverse effects, indicating that PRP may be an effective treatment option for this condition.
12 citations
,
September 2020 in “Stem cell research & therapy” This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.
11 citations
,
April 2013 in “Journal of Proteomics” This study identified proteins that are differentially expressed in balding versus non-balding dermal papilla cells, potentially aiding the understanding and treatment of androgenetic alopecia.
10 citations
,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
7 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study found that the prevalence of androgenetic alopecia was significantly higher among smokers compared to nonsmokers, though the severity wasn't linked to smoking intensity.
7 citations
,
February 2019 in “International Journal of Dermatology” This review discusses factors influencing hair pigmentation and the etiology of canities, noting the lack of clarity in underlying mechanisms and calling for further research on treatment options.
7 citations
,
June 2024 in “Communications Medicine” In this study, researchers analyzed spaceflight data from various sources and found that skin issues during spaceflight are linked to DNA damage, mitochondrial dysregulation, and gene alterations, while also highlighting the skin's adaptability post-flight.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.
6 citations
,
September 2020 in “Advanced Biology” This study found that using the OptoTrkA system to control TrkA activity with blue light enhanced proliferation, migration, and differentiation of hair-follicle-derived stem cells into neuronal and glial cells.
5 citations
,
January 2016 in “Genetics and Molecular Research” This study identified 617 differentially expressed genes in cashmere goat hair follicles, which are involved in key biological processes and provide insights into hair follicle development.
4 citations
,
October 2022 in “Frontiers in public health” In this study on C57BL/6 mice, researchers found that cadmium chloride exposure led to metabolic disruption, accelerated skin aging, and impaired hair regeneration, with more severe effects observed at higher doses.
4 citations
,
January 2018 in “Cosmetics” This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.
4 citations
,
June 2013 in “The Journal of Rheumatology” This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
3 citations
,
August 2014 in “Cellular reprogramming” This study found that multipotent neural crest stem cells from hair follicles require a full set of reprogramming factors for induced pluripotent stem cell induction, similar to fibroblasts.
2 citations
,
January 2017 in “Journal of Pigmentary Disorders” This study explores the complex and not yet fully understood causes of premature hair greying, noting genetic factors such as Pax3 and MITE genes, potential defects in melanin transfer, and associations with certain syndromes, while stating that effective treatments are currently lacking.
2 citations
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March 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study suggests that maternal hyperandrogenism and insulin resistance may induce ferroptosis in the gravid uterus and placenta in rats, but through distinct molecular mechanisms.