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Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

Different types of skin fibroblasts have unique roles in skin health and disease.

New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Selective breeding can enhance immunity in dairy cattle.

The document is a detailed medical reference on skin and genetic disorders.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Three-dimensional culture helps dermal papilla cells grow new human hair follicles.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

New treatments for male hypogonadism are effective and should be personalized.

Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.

Understanding how acne develops in different diseases could lead to new treatments.

The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Mice with human skin protein K8 had more skin problems and cancer.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.

Mutations in the CYP21A2 gene are not a major factor in causing PCOS.

A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.

The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.

Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.