research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
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research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
research Chemotherapy of Psoriasis and Other Skin Disorders with Oral Retinoids
Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
research Intermittent Low-Dose Finasteride Is as Effective as Daily Administration for the Treatment of Hirsute Women
Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.
research In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
research Guidelines for the Use of Acitretin in Psoriasis
Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
research The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers
This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
research A Missing Piece: The Spiny Mouse And The Puzzle Of Menstruating Species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Final Report on the Safety Assessment of Hypericum Perforatum Extract and Hypericum Perforatum Oil
St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.
research Anticonvulsant-Induced Cutaneous Reactions
Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.
research Pharmacodynamics of Minoxidil as a Guide for Individualizing Dosage Regimens in Hypertension
research Minoxidil: Hemodynamic and Clinical Experiences with a New Peripheral Vasodilator
Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
research Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms Behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin with Marilex in Pattern Hair Loss and Telogen Effluvium
Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Squarticles as Nanoantidotes to Sequester Overdosed Antidepressants for Detoxification
Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.
research A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)
Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.
research The Use of Topical Minoxidil to Accelerate Nail Growth: A Pilot Study
Applying 5% minoxidil to fingernails can significantly increase their growth rate.
research Special Focus Issue: Transdermal, Topical, and Follicular Drug Delivery Systems
New drug delivery systems improve treatment effectiveness and patient experience.
research Theoretical Investigation of the Conformational Space of Baicalin
The study found that baicalin has different stable shapes in gas and water, with two shapes better for interacting with positive charges in water.
research Development and Evaluation of Crystalline Inclusion Complex of Finasteride Using Electrospraying as a Novel Approach
Created finasteride complex to increase water solubility and drug release.
research Thermodynamic Modeling of the Gas-Antisolvent Process for Precipitation of Finasteride
The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.
research Drug Repurposing in Dermatology: Molecular Biology and Omics Approach
Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.
research Cutaneous Drug Reactions
Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
research Determination of Adulteration in Hair Serums by LC-HRMS
A new method found unlisted drugs in two popular hair serums, posing a health risk.
research Glossary
research Anti-Anginal and Beta-Adrenoceptor Blocking Drugs
Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.
research Poster Abstract: Novel Dissolving Microarray Patches for Intradermal Delivery of Finasteride
Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.