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This study found that the pH dependency of rat steroid 5α-reductase type II isozyme significantly affects its kinetic properties, including Vmax and Km, suggesting past discrepancies in literature may arise from these pH variances during assays.

This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.

This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.

This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.

This study describes a method to extract and characterize keratin particles from human hair, finding they can encapsulate the anticancer drug Paclitaxel with significant efficiency, releasing it in a pH-dependent manner potentially beneficial for targeted cancer treatment.

This study demonstrated that stress inhibited hair growth in mice, likely through substance P-dependent activation of immune cells, highlighting a brain-hair follicle connection.

This study observed that hair properties vary by ethnicity, influenced by genetic, environmental, and cultural factors, and noted that ethnicity-dependent differences in surface charge and other properties warrant further investigation.

This study used melamine formaldehyde particles to measure a pH gradient along the hair shaft, showing a significant pH decrease from the hair sheath to the external shaft.

In this study, researchers synthesized biomedical polyurethanes incorporating curcumin and varying PEG content to enhance water solubility and control curcumin release, finding that higher PEG content improved hydrophilicity, swelling, and degradation, while maintaining excellent antioxidant and antibacterial activities, suggesting promise for biomedical applications.

This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.

This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.

This study found that the primary mechanism behind hair relaxation in Afro-hair is the alkali-induced denaturation of helical filaments, leading to spontaneous straightening.

This study suggests that minoxidil may serve as a suitable reference drug for high permeability classification in the Biopharmaceutics Classification System due to its consistent permeability across different intestinal segments and pH levels.

This study found that hair tonics containing clove ethanol extract increased hair growth in rabbits, with a dose-dependent effect observed at varying concentrations of the extract.

This study observed that the binding of certain hormones in rat skin varies cyclically with the hair cycle phases, with testosterone showing maximum binding in the catagen phase.

This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.

This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.

This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.

This study found that the ethanol extract of Eclipta alba significantly reduced gastric lesions and enhanced gastroprotective activity in ulcer-induced rats, suggesting potent antisecretory effects potentially linked to antioxidant properties.

This study found that a rosemary extract hair tonic at concentrations up to 15% effectively promotes hair growth in male Wistar rats, achieving longer and thicker hair compared to minoxidil 2%, and causing fewer side effects.

This study explored a novel finasteride-loaded nanoparticle gel for treating alopecia areata, finding that it significantly increased hair follicle number and size without causing skin irritation, presenting an effective alternative to traditional minoxidil treatments.

This chapter reviews the recent understanding of carbonic anhydrase VI's functions, including its role in biological processes, but presents no new experimental results.

This study found that maternal iron-restricted diets increased alopecia incidence in IL-10-deficient mouse pups with mast cells, implicating mast cells as potential effectors in this process.

This study observed similar D2-40 expression in scarring and nonscarring alopecia, with some increase in scarring cases, suggesting possible Fos-dependent mechanisms, though more research is needed for definitive conclusions.

This review discusses the role of reactive oxygen species in regulating oscillating apoplastic pH gradients and growth in plant root hairs and pollen tubes, reporting no new experimental results.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

In this study, mice on a methionine-deficient diet experienced hair loss, which was not remedied by homocysteine supplementation; hair regrowth only resumed after methionine was reintroduced, suggesting dietary methionine is essential for hair maintenance.

This review discusses various targets for treating prostate cancer and benign prostatic hyperplasia and reports on recent studies of new compounds and 5α-reductase inhibitors, but provides no new experimental results.

This study found that L-type channel blockers can induce hair growth in Timothy syndrome by overcoming delays in anagen phase, suggesting a potential therapeutic role for tissue regeneration.

This study found that a gene from hamster flank organs is indirectly regulated by androgens, despite lacking direct androgen responsive elements, indicating involvement of androgen-dependent transcription factors.