research Insulin Resistance as a Risk Factor for the Development of Type 2 Diabetes Mellitus: A Systematic Approach
Insulin resistance increases the risk of developing type 2 diabetes and other health issues.
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research An X-Linked Gene Involved in Androgenetic Alopecia: A Lesson to Be Learned from Adrenoleukodystrophy
Gene linked to common hair loss found, may lead to new treatments.
research Hot Topics in Pediatric Dermatology
Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.
research Metformin: An Old Medication of New Fashion: Evolving New Molecular Mechanisms and Clinical Implications in Polycystic Ovary Syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research Lichen Planopilaris Treated With a Peroxisome Proliferator-Activated Receptor Gamma Agonist
A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.
research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes
The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
research Inherited Ichthyosis: Syndromic Forms
Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
research Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
FA2H is essential for normal fur and sebum production in mice.
research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research A Glutathione-Dependent Control of the Indole Butyric Acid Pathway Supports Arabidopsis Root System Adaptation to Phosphate Deprivation
Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.
research Frontal Fibrosing Alopecia: A Review
Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
research Sebaceous Gland Abnormalities in Fatty Acyl CoA Reductase 2 (Far2) Null Mice Result in Primary Cicatricial Alopecia
Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
research Banding Pattern on Polarized Hair Microscopic Examination and Unilateral Polymicrogyria in a Patient With Steroid Sulfatase Deficiency
A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Expression of E-SOD, GPX5 mRNAs and Immunoexpression of Cu/ZnSOD in Epididymal Epithelial Cells of Finasteride-Treated Rats
Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.
research Novel ABCD1 Gene Mutation in Adrenomyeloneuropathy with Hypoplasia and Agenesis of the Corpus Callosum
Researchers found a new ABCD1 gene mutation linked to a rare brain and nerve disorder with unusual brain changes.
research Function and Interactions of the Ysc84/SH3yl1 Family of Actin- and Lipid-Binding Proteins
The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.
research The Association of Urolithiasis and Androgenetic Alopecia
Hair loss linked to kidney stones in people under 60.
research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Stimulation by Exosomes from Hypoxia-Preconditioned Hair Follicle Mesenchymal Stem Cells Facilitates Mitophagy by Inhibiting the PI3K/AKT/mTOR Signaling Pathway to Alleviate Ulcerative Colitis
Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.
research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
research Botanical Treatment for Polycystic Ovary Syndrome
Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.
research Spermidine/Spermine-N1-Acetyltransferase: A Key Metabolic Regulator
SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
research Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice
Glycerol is essential for skin hydration in mice without sebaceous glands.
research The Mechanisms and Functions of Interorganelle Interactions
Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research The Genomic Variation in Textured Hair: Implications in Developing a Holistic Hair Care Routine
Afro-textured hair needs personalized care due to its unique genetic traits.
research Bachmann–Bupp Syndrome and Treatment
DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
research Frontal Fibrosing Alopecia: Study of 12 Cases in Argentina
The study found that the average age of women diagnosed with Frontal Fibrosing Alopecia in Argentina is higher than in other countries, but their symptoms are similar.