January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.
September 2014 in “Journal der Deutschen Dermatologischen Gesellschaft” Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
December 2011 in “InTech eBooks” Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.
May 2009 in “The American Journal of Dermatopathology” Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
May 2007 in “Dermatologic Therapy” Hair care practices like using relaxers and tight braiding can lead to permanent hair loss in black women.
November 2001 in “Dermatologic Surgery” Galea fixation is a safe and effective way to remove bald scalp with minimal scarring and reduced stretch-back.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
1514 citations,
December 2011 in “Fertility and sterility” Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
474 citations,
January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
441 citations,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
405 citations,
May 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.
378 citations,
November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
356 citations,
September 2014 in “Journal of Clinical Research in Pediatric Endocrinology” Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.
343 citations,
October 2015 in “Endocrine Practice” The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
291 citations,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
275 citations,
March 1999 in “Journal of The American Academy of Dermatology” Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
254 citations,
September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
249 citations,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
243 citations,
September 2016 in “Dermatology and Therapy” Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.
237 citations,
December 2001 in “Urology” Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
220 citations,
August 1988 in “Clinical endocrinology” Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
204 citations,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
202 citations,
June 2005 in “Aaps Pharmscitech” Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
191 citations,
February 2002 in “Archives of Dermatology” Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.