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    Glossary PDE5 inhibitors

    block enzyme to improve blood flow in certain conditions

    PDE5 inhibitors, or phosphodiesterase type 5 inhibitors, are a class of medications that block the enzyme PDE5, which is involved in regulating blood flow in the body. By inhibiting this enzyme, these drugs help to relax blood vessels and improve blood flow, making them effective treatments for conditions like erectile dysfunction and pulmonary arterial hypertension.

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    Research 30 of 520

    1. FDA approves label addition for PDE-5 inhibitor Urology Times eNews · 2013
    2. Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS) Figshare · 2026
    3. Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS) Figshare · 2026
    4. Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS) The Aging Male · 2026
    5. PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION The Journal of Urology · 2018
    6. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013 · 2152 citations
    7. Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2006 · 14 citations
    8. Adverse effects of common medications on male fertility Nature Reviews Urology · 2015 · 77 citations
    9. Investigation, treatment and monitoring of late‐onset hypogonadism in males: ISA, ISSAM, and EAU recommendations Andrology · 2005 · 280 citations
    10. Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia Frontiers in Pharmacology · 2020 · 35 citations
    11. Wider clinical applications of fumaric acid esters: A useful option in psoriasis patients with multiple sclerosis Journal of The American Academy of Dermatology · 2015 · 1 citations
    12. Medical management of benign prostatic hyperplasia Cleveland Clinic journal of medicine · 2024
    13. Study of QuantiFERON’S conversion/reversal phenomena in patients with psoriasis during biological treatment Journal of The American Academy of Dermatology · 2015
    14. Evaluation of risk of SSRI-associated impotence and low libido in men exposed to finasteride Journal of The American Academy of Dermatology · 2016
    15. Risks and side effects in the medical management of benign prostatic hyperplasia Prostate International · 2023 · 26 citations
    16. Sexual Dysfunction Related to Drugs: a Critical Review. Part V: α-Blocker and 5-ARI Drugs Pharmacopsychiatry · 2015 · 15 citations
    17. Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells Biomolecules & Therapeutics · 2019 · 9 citations
    18. 1194: The Long Term Effects of Doxazosin, Finasteride, and the Combination on Sexual Function in Men Participating in the MTOPS Study The Journal of Urology · 2004 · 8 citations
    19. Impact of Hormones on Female Sexual Function and Dysfunction Female pelvic medicine & reconstructive surgery · 2011 · 3 citations
    20. 311 Novel Penile Ultrasound Technique to Explain Mechanism of Erectile Dysfunction (ED) in Young Patients using Finasteride for Androgenic Alopecia The Journal of Sexual Medicine · 2018 · 1 citations
    21. Sexual Medicine Reviews—The Premiere Review Journal for the Field of Sexual Medicine Sexual Medicine Reviews · 2015 · 1 citations
    22. The urologic impact of long-term finasteride 1-mg use for androgenic alopecia: a matched-cohort database analysis World Journal of Urology · 2026
    23. IP28-24 RISK OF ERECTILE DYSFUNCTION AMONG REPRODUCTIVE-AGED MEN FOLLOWING LOW-DOSE FINASTERIDE USE FOR ANDROGENETIC ALOPECIA: A PROPENSITY-MATCHED COHORT STUDY The Journal of Urology · 2026
    24. MP11-05 THE UROLOGIC IMPACT OF LONG-TERM FINASTERIDE-1 MG USE FOR ANDROGENIC ALOPECIA: A MATCHED-COHORT DATABASE ANALYSIS The Journal of Urology · 2025
    25. The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease Yearbook of Urology · 2013
    26. Faculty Opinions recommendation of Treatment of recurrent priapism in sickle cell anemia with finasteride: a new approach. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2010
    27. Patient-convenient Long-term Alopecia Treatment via PLGA Microsphere-Loaded Candlelit Microneedle Journal of Materials Chemistry B · 2025
    28. 5-Alpha-Reductase Inhibitors and Combination Therapy Urologic Clinics of North America · 2016 · 15 citations
    29. 8 Finasteride-Associated Suicide and Depression in Men Treated for Hypogonadism and Impotence The Journal of Sexual Medicine · 2022
    30. Most recent findings of curative drugs for lower urinary tract symptoms in clinical practice Nihon Yakuri Gakkai nenkai yoshishu · 2019