This study observed that melatonin treatment reduced cellular damage and apoptosis in the intestinal epithelium of rats with acute necrotizing pancreatitis compared to untreated rats.
1 citations
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October 1984 in “Clinics in dermatology” This article discusses the psychological impact of skin imperfections and suggests establishing a Cosmetic Dermatology Service within public health systems to address these issues ethically.
April 2023 in “Journal of Investigative Dermatology” 3D ultrasound can detect hair follicle changes and disease phases in alopecia areata.
December 2025 in “International Journal of Innovative Technologies in Social Science” This study found that disruptions in the skin microbiome, known as dysbiosis, play a significant role in various skin conditions, including atopic dermatitis, psoriasis, acne, rosacea, skin cancer, and impaired wound healing, by altering immune responses and barrier functions.
11 citations
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June 1985 in “Journal of cutaneous pathology” This review details pathologic changes in hair follicles, such as infundibular hyperkeratosis and inflammation, but offers no new diagnostic results.
This article reviews pathologic mechanisms causing hair changes in women on hormonal contraceptives or pregnant and reports no new study results; hormonal effects on the hair cycle stages are suggested.
17 citations
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July 2014 in “Our Dermatology Online” In this study of elderly patients at an Indian medical center, researchers found that xerosis was the most common physiological skin change and pruritus was the most frequent complaint.
19 citations
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October 2019 in “Dermatology Practical & Conceptual” This review discusses the expanding applications of dermoscopy in dermatological diagnosis beyond its initial use for detecting dysplastic nevi and reports no new clinical results.
June 2026 in “Wiadomości Lekarskie” This study found that patients undergoing endocrine surgery commonly experienced hormonal disorders and dermatologic complications, particularly those with hormonal imbalances, highlighting the importance of dermatologic surveillance and aesthetic rehabilitation in postoperative care to improve quality of life.
12 citations
,
February 1986 in “PubMed” This study found that newborn mice given 6-aminonicotinamide developed skin, intestinal, and central nervous system lesions, offering insights into the mechanisms of pellagra.
8 citations
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April 2014 in “Clinical and Experimental Dermatology” This study suggests that eruptive vellus hair cysts often have atypical pathological changes and likely originate from the infrainfundibulum and sebaceous duct based on keratin expression analysis.
1 citations
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June 2008 in “The Journal of Urology” This letter to the editor references a study on using dihydrotestosterone gel before hypospadias surgery but itself contains no new findings.
April 2026 in “Biomedicines” This study introduces a novel holistic treatment approach for keloid that combines systemic therapies, including Traditional Chinese Medicine, with local interventions to target the inflammatory microenvironment and keloid predisposition for improved management and prevention of recurrence.
13 citations
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September 2020 in “International Journal of Molecular Sciences” This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.
12 citations
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May 1989 in “Postgraduate Medicine” This article discusses treatments for male pattern baldness, noting that minoxidil is effective for improving baldness at the scalp vertex in young men, and reports no new clinical results.
January 2014 in “Progress of Digestive Endoscopy” This case report describes a 60-year-old woman with Cronkhite-Canada syndrome whose symptoms and polyposis improved following prednisolone therapy, but emphasizes the need for periodic digestive tract screening due to associated cancer risks.
May 2026 in “Theranostics” This study found that the DKK3-CKAP4 signaling axis is involved in fibroimmune remodeling in androgenetic alopecia and that targeting this pathway may restore a regenerative hair follicle environment, offering a potential therapeutic strategy to counteract hair follicle miniaturization.
30 citations
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January 2015 in “BioMed Research International” Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
October 2021 in “Case Reports in Veterinary Medicine” This veterinary case study of a dog with myxedema coma found clinical and pathologic changes including severe thyroid atrophy and marked atherosclerosis consistent with the diagnosis.
72 citations
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February 2011 in “American Journal of Biological Anthropology” This study observed that eliminating positional error in hair segment analysis can improve understanding of changes in isotopic composition, aiding the identification of pathological conditions and dietary patterns.
6 citations
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July 2013 in “Experimental and Therapeutic Medicine” This study found that topical ginsenoside Rg1 may protect skin from UVB-induced damage in mice by reducing pathological changes and modulating cytokine mRNA expression associated with inflammation and immune response.
November 2022 in “International Journal of Trichology” This review discusses alopecia in elderly patients, differentiating between normal hair aging and pathological changes, and reports no new clinical results; the authors aim to guide clinicians in management.
3 citations
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August 2017 in “Journal of evolution of medical and dental sciences” In this descriptive study, elderly patients most commonly presented with skin wrinkling, xerosis, and eczematous conditions, highlighting the difficulty in distinguishing normal age-related from pathological skin changes.
January 2026 in “Veterinarski glasnik” In this case report, researchers highlighted the importance of age-appropriate interpretation of clinical findings in an orphaned Bosnian Mountain Horse foal, observing that physiological changes rather than pathological ones contributed to variations in blood and biochemical parameters, while also diagnosing skin lesions of distinct origins.
December 2025 in “Brazilian Journal of Hair Health” This integrative review developed a Spiral Model to better represent human hair follicle dynamics and aging, which may assist in distinguishing natural aging from pathological changes and improving trichological interventions.
January 2019 in “International Journal of Research in Dermatology” This study observed that among elderly patients, pruritus was the most common cutaneous complaint, while physiological changes like wrinkling and pathological changes such as skin tumors and eczemas were frequent findings.
August 2016 in “Journal of Dermatology” This research successfully established a novel mouse model for anagen effluvium using BrdU treatment, which induced hair loss and pathological changes mimicking human symptoms.
48 citations
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September 2011 in “British Journal of Dermatology” This study found that DNA methylation and histone modification status were altered in peripheral blood mononuclear cells of patients with alopecia areata, suggesting these changes may contribute to the disease's pathological immune responses.
6 citations
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September 2024 in “Cell Communication and Signaling” This study reviews the structural and functional aspects of cell-cell and cell-matrix junctions in sebocytes, emphasizing their roles in sebocyte differentiation and sebum secretion, and how these processes may change in pathological conditions, potentially providing insights for new skin disease therapies.
2 citations
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May 2017 in “Springer eBooks” Pregnancy can cause skin changes and affect existing skin conditions, with limited treatment options due to the need for fetal safety.