3 citations
,
April 2019 in “Human & Experimental Toxicology” This study found that finasteride caused adverse effects on liver, kidney, and heart tissues in female mice, raising concerns about its potential use in females for treating androgenetic alopecia.
18 citations
,
September 1990 in “Veterinary Dermatology” This study in SPF lambs found that primary and secondary orf virus infections trigger similar skin responses, but the primary infection caused a more severe and prolonged reaction.
20 citations
,
June 1985 in “Toxicologic Pathology” In this study, prolonged high-dose steroid treatment in rats caused several pathological changes, some of which regressed, particularly improvements in mammary gland tumors and pituitary-related symptoms, after stopping treatment.
2 citations
,
May 2023 in “Experimental dermatology” In this study, researchers used advanced four-dimensional optical imaging techniques to observe changes in skin afflicted with acne, finding increased epidermal thickness, keratinized hair follicles, inflammation, and aggregated blood flow, helping to distinguish between inflammation and reparative phases of acne progression.
June 2026 in “Journal of Advances in Biology & Biotechnology” In this study conducted at the Veterinary Clinical Complex in Bikaner, Rajasthan, researchers found that among 240 canine dermatitis cases, 25 dogs had demodicosis, characterized by various hematological and serum biochemical changes, and distinctive histopathological alterations in skin samples.
September 2020 in “Nature, Environment and Pollution Technology/Nature, environment and pollution technology” This study found that Wistar rats fed with grass extracts from mining areas accumulated trace metals, particularly in the spleen, leading to organ pathology and signs of toxicity.
This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.
March 2023 in “Clinical, cosmetic and investigational dermatology” This study suggests that IL-33 promotes hair follicle changes and T cell infiltration in psoriatic mice and humans, contributing to psoriatic alopecia.
1 citations
,
January 2023 in “International journal of molecular sciences” This study found that S. scabiei infestation in rabbits leads to epidermal thickening possibly due to apoptosis-related proliferation and keratinization of the skin.
March 2024 in “Journal of biobased materials and bioenergy” In this study, tea tree oil was found to have substantial antibacterial activity and promote proliferation and migration of hair follicle stem cells in vitro, indicating potential benefits for treating scalp alopecia areata.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
2 citations
,
June 2001 in “American Journal of Pathology” This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.
November 2025 in “Contribuciones a las Ciencias Sociales” This study suggests that incorporating laboratory tests into routine aesthetic procedures may improve result predictability and reduce risks, underscoring the importance of professional expertise in the evaluation process.
This study examines the role of T. verrucosum in bovine dermatitis, revealing various pathological skin changes such as hyperkeratosis, necrotic hair follicles, and severe neutrophil aggregation in cows from Diyala Governorate.
71 citations
,
February 2006 in “Clinics in Dermatology” This review discusses the physiological skin changes during pregnancy and reports no new clinical results, emphasizing the importance of distinguishing these changes from pathological conditions.
41 citations
,
October 2017 in “International Journal of Women's Dermatology” This review provides an overview of the physiologic skin changes during pregnancy but reports no new findings, emphasizing the need for physicians to distinguish between benign and potentially pathological conditions.
12 citations
,
October 2023 in “International Journal of Molecular Sciences” This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.
December 2023 in “International journal of research in dermatology” In this study, physiological skin changes like linea nigra (84.4%) and striae distensae (78.4%) were most common in pregnant women, while pathological changes were shown to be significantly associated with gravida and gestational age.
2 citations
,
March 1976 in “PubMed” In this study, Neogynon was found to be 100% effective as a contraceptive, with no observed failures in 3129 cycles among 184 women, while side effects included changes in endometrial patterns and some central nervous system effects.
March 2026 in “Biomedicines” This study found that the Antera 3D® system provided an objective and sensitive method for assessing pediatric pathological scars, capturing significant changes in pigmentation, vascularity, and volume, compared to the traditional Vancouver Scar Scale and dermoscopy, which showed varied sensitivities across different scar parameters.
This study utilized 3D ultra-high frequency ultrasound to effectively detect different disease phases of alopecia areata by visualizing hair follicle structures and identifying unique pathological signs, offering a promising non-invasive diagnostic tool that surpasses conventional methods.
3 citations
,
January 2018 in “Indian Dermatology Online Journal” This study found that normal physiological cutaneous changes were the most common skin changes during pregnancy in Northeast India, while specific dermatoses were rare and not significantly influenced by ethnicity or geography.
70 citations
,
February 2025 in “Journal of Ovarian Research” This review provides an analysis of the physiological and pathological aspects of polycystic ovary syndrome, emphasizing endocrine, metabolic, and inflammatory dimensions, but reports no new clinical results.
May 2021 in “GSC Advanced Research and Reviews” This review discusses recent advances in the understanding of follicular melanogenesis and its pathological changes, particularly how these changes are associated with specific disease phenotypes, but it reports no new results.
3 citations
,
October 2020 in “International journal of radiation research” This study found that while flour irradiation disrupted the physiology of Tribolium confusum, it also caused significant weight loss and biochemical changes in rats fed on irradiated flour.
March 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” Among elderly individuals attending a dermatology department, this study found that common skin conditions were wrinkles, xerosis, and seborrheic keratosis, with infections and eczema being the most frequent pathological conditions, highlighting the need for public health measures targeting geriatric dermatoses.
February 2026 in “Dermatology and Therapy” This study observed that sonidegib led to a meaningful clinical response in a real-world Chinese cohort with locally advanced basal cell carcinoma, although pathological biopsy remains essential to confirm tumor clearance due to false positives in noninvasive assessments.
September 2021 in “CRC Press eBooks” This article reviews various skin changes and conditions during pregnancy, noting that while many are normal, some can become pathologic, but it reports no new research findings.
51 citations
,
March 2001 in “Clinics in dermatology” This study found that bleach treatments significantly increased hair surface roughness and decreased Young's modulus, indicating marked changes in hair's molecular structure which may affect future hair-care product formulation.
35 citations
,
January 2009 in “Indian Journal of Dermatology, Venereology and Leprology” Older adults commonly experience wrinkles, itchy skin, psoriasis, fungal infections, skin growths, grey hair, hair loss, and nail ridging, but no skin cancer was found in this group.