4 citations
,
July 2024 in “Biomolecules” This review suggests systemic changes in polycystic ovary syndrome may increase the risk of neurodegeneration, potentially linking it to Alzheimer's disease through common pathways affecting tryptophan metabolism.
2 citations
,
June 2024 in “Journal of Clinical Medicine” This study identifies various nail changes in alopecia areata, which can affect quality of life, and suggests that while spontaneous improvement is possible, further research is needed to refine treatment strategies.
1 citations
,
January 2023 in “Science Advances” This study found that bacterially induced metabolic changes in stem cells can enhance skin and hair follicle regeneration in both mice and humans, suggesting potential strategies for improving recovery after injury.
September 2022 in “Dermatology and therapy” This review discusses the pathological factors and comorbidities associated with androgenetic alopecia and reports no new clinical results, emphasizing the need for improved understanding and treatment in clinical practice.
9 citations
,
January 2014 in “World journal of clinical cases” This review discusses the clinical and pathologic features of follicular contact dermatitis, highlighting neomycin as a potential cause, and reports no new clinical results.
21 citations
,
December 2019 in “PloS one” In this study, the authors concluded that the VCD-induced follicular depletion rat model can effectively simulate the perimenopause transition, with hormonal changes distinguishing early/mid-transition from late transition to estropause.
15 citations
,
November 2017 in “JAAD Case Reports” This study reports no known changes in hair pigmentation associated with brentuximab vedotin, despite its various other documented adverse effects.
114 citations
,
February 2023 in “International Journal of Molecular Sciences” This review discusses the relationship between skin microbiome changes and conditions such as ageing and skin disease, emphasizing the need for further research, but reports no new findings.
55 citations
,
April 2022 in “Journal of Molecular Medicine” This review discusses the relationship between aging, chronic inflammation, and immunosuppression, suggesting that these interconnected processes may contribute to tumorigenesis and premature aging, but reports no new experimental results.
26 citations
,
July 2012 in “Endocrine Connections” This study found that mitotane causes specific changes in cortisol metabolism, including increased excretion of certain metabolites, which may influence cortisol bioavailability without hindering early detection of adrenocortical carcinoma recurrence.
20 citations
,
November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.
February 2026 in “International Journal of Advanced Biochemistry Research” This study reports that dogs with dermatoses linked to hypothyroidism displayed a significant incidence of specific haematological and biochemical alterations, such as elevated cholesterol and triglyceride levels and reduced thyroid hormones, compared to healthy dogs, with Labrador Retrievers showing the highest breed predisposition.
March 2021 in “Medico-Legal Update” In this study, no significant change in androgen receptor gene expression was found in females with recurrent spontaneous abortion, but a mutant genotype may offer some protection against the condition.
21 citations
,
February 2021 in “Frontiers in Endocrinology” This review explores the potential impact of hormonal changes during aging on benign prostate hyperplasia-related urinary symptoms and metabolic syndrome, highlighting the hypothesis of a male PCOS-equivalent but reports no new clinical results.
15 citations
,
January 2020 in “ILAR Journal” This review discusses the occurrence and impact of background histopathologic changes in nonhuman primate research, emphasizing the importance of understanding these factors to enhance study validity and interpretation.
31 citations
,
October 2010 in “Progress in lipid research” This review discusses the role of LPA(3) in embryo implantation and its genetic connection with prostaglandin signaling, but reports no new clinical results.
February 2026 in “Journal of Aesthetic Medicine” This narrative review concluded that facial aging involves complex anatomical changes that require multimodal rejuvenation approaches, integrating fillers, collagen stimulators, botulinum toxin, and energy-based devices for effective results, while emphasizing the need for scientific evidence and patient safety in aesthetic treatments.
This study found that hair and nails can effectively measure hormone changes such as testosterone, estrogen, and progesterone during the peripubertal period in dogs, with variations observed between males and females at specific developmental stages.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that anabolic steroid use combined with plakoglobin deficiency caused pathological atrial electrical remodeling in young male mice, suggesting a higher risk of atrial myopathy for males with desmosomal gene variants.
December 2019 in “Orvostudományi Értesítö” This article reviews treatment approaches for polycystic ovary syndrome, highlighting lifestyle changes, medications like metformin for insulin resistance, and fertility therapies, acknowledging the complexities and contraindications involved.
May 2023 in “British Journal of Dermatology” COVID-19 can cause long-term skin problems and has changed how skin doctors work.
9 citations
,
May 2023 in “Stem Cell Research & Therapy” This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.
9 citations
,
December 1981 in “International Journal of Dermatology” The document concludes that early diagnosis is key for treating common baldness in women, but reassurance is often the best approach as hair thinning can be a normal part of aging.
November 2025 in “BMC Genomics” This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.
218 citations
,
September 2012 in “Gastroenterology” This review discusses the role of epigenetics in colorectal cancer and explains how changes like DNA methylation impact tumor development, but it reports no new results.
103 citations
,
January 2009 in “Carbon” This study found that carbon nanotube impurities induced immunological toxicity in mice, whereas purified nanotubes showed good biocompatibility, suggesting high-temperature thermal treatment may improve nanotube biocompatibility.
22 citations
,
September 2019 in “Trends in Immunology” This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.
14 citations
,
January 2018 in “Scientific reports” This study demonstrated that bioluminescence imaging of NG2+ cells in transgenic rats allows in vivo monitoring of hair follicle cycles to study hair growth and follicle regeneration.
9 citations
,
January 2021 in “Mediators of Inflammation” In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.