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This study observed early cardiac effects in young minipigs following high-dose doxorubicin chemotherapy, with a decrease in heart function and changes in cardiac MRI measurements compared to controls.

In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.

This discussion reviews the lack of long-term clinical studies on metformin's cardiovascular benefits in women with polycystic ovary syndrome, advocating for lifestyle changes to improve insulin sensitivity.

This review discusses the management of long-term risks in women with polycystic ovary syndrome, recommending lifestyle changes to improve insulin sensitivity over relying solely on metformin, and reports no new clinical results.

This review discusses the lack of long-term clinical studies on metformin's cardiovascular benefits in women with polycystic ovary syndrome, highlighting lifestyle changes as a crucial management strategy for reducing associated risks.

This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.

This article discusses how androgenic alopecia, commonly known as pattern hair loss, can have significant psychological effects on both men and women, and it highlights homeopathy as a treatment option that considers both psychological and pathological impacts.

This study established a pluripotent stem cell line from a patient with androgenetic alopecia, which can potentially be used to study the disease's pathological mechanisms.

This article proposes five different mechanisms for telogen effluvium, supported by clinical findings, based on changes in different phases of the hair cycle.

This study found that the BMP antagonist noggin induces hair growth in postnatal skin by neutralizing BMP4's inhibitory activity, potentially mediated by changes in Shh expression.

This study suggests that the use of 5α-reductase inhibitors in men may be associated with macular abnormalities, characterized by cystoid changes and foveal cavitation, potentially progressing to more severe defects.

This study discusses incidental findings of syringomas and syringomatous proliferations in areas of scalp alopecia, suggesting they may be secondary to reactive changes from subclinical alopecia.

This article reviews challenges in diagnosing new-onset SLE during pregnancy, emphasizing the complexity of distinguishing it from normal pregnancy changes and preeclampsia, and reports no new results.

This letter to the editor discusses data from a study on troglitazone for lipodystrophy, noting significant increases in subcutaneous fat without dietary changes.

In this study, researchers used tissue clearing techniques on human skin and scar tissue for the first time to render them optically transparent, with the aim of revealing atypical structures and improving protocols for observing scar tissue changes.

This study reviews the embryological origins, anatomical and histological structure, and key functions of the skin, emphasizing its protective, sensory, and regulatory roles, as well as the social and psychological impacts of post-lesion changes.

Immune system changes may contribute to female pattern hair loss.

This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.

This study found that DNA methylation changes in granulosa cells from PCOS patients affect gene expression related to insulin resistance, fat cell differentiation, and steroid metabolism, suggesting an epigenetic contribution to PCOS pathogenesis.

This review summarizes recent pathological discoveries related to chemical leukoderma and chemical-induced vitiligo, especially focusing on rhododendrol, a chemical responsible for a significant outbreak affecting around 20,000 individuals in Japan and Asia.

Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.

This review discusses how skin changes like acanthosis nigricans and psoriasis can indicate metabolic syndrome components such as insulin resistance and dyslipidemia, suggesting a potential role for early diagnosis and treatment in reducing cardiovascular risks associated with the syndrome.

This abstract does not provide specific findings or results.

Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.

In this study, researchers identified key transcriptome changes in male androgenetic alopecia hair follicles, suggesting that HIF-1 pathway genes and Wnt pathway inhibitors could be potential therapeutic targets.

This article discusses scalp neuropathy in androgenetic alopecia and suggests that changes in tactile sensation due to Aβ fibers and increased nociception from circ-HTMR may be involved.

This study found that pregnant women experience a broad array of skin changes, with pigmentary alterations and striae being the most common physiological changes observed.

This review discusses the commonly observed pathological findings in progeroid mouse models and highlights the importance of understanding mouse strain backgrounds and progeria-related phenotypes for accurate pathology data interpretation.

This review discusses the changes in hair follicles with aging, particularly graying due to decreased melanocyte activity, and suggests potential for hair repigmentation under certain conditions, but reports no new results.

This study suggests that breast cancer-associated phospholipids may alter the X-ray diffraction pattern of hair, potentially enabling the development of a sensitive and specific screening test for breast cancer.