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September 2017 in “Frontiers in Laboratory Medicine” This review discusses recent research on the relationship between gut microflora and depression, highlighting the potential for new insights into the pathogenesis and treatment of major depressive disorder.
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November 2015 in “European medical journal” This article reviews the complex role of various biological, genetic, and environmental factors in acne pathogenesis and notes no new clinical results.
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October 2014 in “Skin Pharmacology and Physiology” This study found that osteopontin expression was significantly higher in alopecia areata lesions compared to healthy controls, suggesting it may play a role in the disease's pathogenesis.
This case report documents the first instance of Microsporum canis infection in a red fox, successfully treated with ketoconazole, highlighting asymptomatic cats as possible carriers of this pathogen.
1 citations
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January 2002 in “Journal of Clinical Dermatology” This study found that women with chronic telogen effluvium had significantly lower serum ferritin levels and higher TIBC levels compared to normal females, suggesting a potential role for iron stores in the condition's pathogenesis.
August 2026 in “International Journal of Research in Dermatology” This case study reports co-localized vitiligo and alopecia areata on the scalp of a 33-year-old Indian male, with marked improvement following intralesional corticosteroid treatment, suggesting a shared autoimmune pathogenesis.
August 2026 in “Dermatology and Therapy” In this review, researchers outline the characteristics of scalp rosacea, an underrecognized inflammatory dermatosis, describing its multifactorial pathogenesis, diagnostic features, and management strategies, noting its clinical similarities with facial rosacea and the absence of standardized diagnostic criteria or therapeutic guidelines.
June 2026 in “Archives of Dermatological Research” This study observed that PCAT1 and HOTAIR gene expressions were significantly lower in individuals with androgenic alopecia compared to healthy controls, suggesting their potential involvement in the condition's pathogenesis.
March 2026 in “Frontiers in Medicine” In this review, recent studies on muscle atrophy are highlighted, revealing insights into its complex pathogenesis, therapeutic interventions such as hormone therapy, and diagnostic advancements, while emphasizing the need for personalized approaches and addressing challenges like small sample sizes and methodological diversity.
This case study reports a rare instance of both alopecia areata and fixed drug eruption occurring in the same area on a 40-year-old man's beard, triggered by oral paracetamol, highlighting potential shared pathogenic pathways and the isotopic phenomenon.
January 2026 in “Case Reports in Dermatological Medicine” This report identified a family of Iranian siblings with diverse clinical forms of Lichen Planus, suggesting potential genetic and environmental involvement in its pathogenesis.
January 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study observed that male patients with alopecia areata had elevated serum levels of HSP70 and IL-15, with levels increasing alongside disease severity, suggesting these markers are strongly associated with the disease's pathogenesis.
December 2025 in “Skin Appendage Disorders” This review explores the under-researched role of apocrine glands in the human scalp, suggesting they may play a significant part in waste removal, electrolyte balance, interaction with the microbiome, and the pathogenesis of follicular occlusion diseases, despite being often overlooked.
December 2025 in “Scientific Reports” In this study, researchers observed that DHEA-induced PCOS rats experienced significant changes in gut microbiota and metabolic profiles, particularly affecting steroid and lipid metabolism, suggesting the gut-ovary axis may play a role in the pathogenesis of PCOS.
December 2025 in “Research Focus International Scientific Journal” In this study, researchers found that oxidative stress and mitochondrial dysfunction are correlated with the severity of both androgenetic alopecia and alopecia areata, revealing specific differences between alopecia forms, which may serve as important pathogenetic and prognostic indicators.
December 2025 in “Biology Bulletin” In this study, researchers examined the skin of Baikal seals, identifying two main skin pathologies potentially linked to global warming and an unknown viral pathogen, suggesting immune inflammatory processes associated with environmental changes may be affecting these seals.
November 2025 in “Biomedicines” In this review, researchers reported that pyroptosis, a type of inflammatory cell death linked to inflammasome activity, is a key factor in the pathogenesis of alopecia areata and may present new therapeutic opportunities, though most treatments are still in early research stages.
November 2025 in “Journal of Clinical Medicine” This review article explores the potential systemic nature of alopecia areata, highlighting the association with ocular abnormalities and suggesting that shared pathogenic pathways may lead to eye symptoms occurring at younger ages than usual.
This study identified 19 genetic risk loci and 16 potential causal genes related to PCOS, highlighting the role of immune cell-specific mechanisms in its pathogenesis.
September 2025 in “Journal of Clinical Medicine” This study found that patients with vitiligo and alopecia areata had significantly higher serum granulysin levels compared to healthy controls, indicating a potential pathogenic role and suggesting that elevated levels may serve as a biomarker for monitoring disease activity, particularly in active vitiligo cases.
September 2025 in “International Journal of Latest Technology in Engineering Management & Applied Science” This study reviewed Ayurvedic texts and concepts related to hair loss, known as Indralupta, its pathogenesis involving vitiated doshas and blood, and Ayurvedic treatment approaches, highlighting its differentiation from khalitya, where hair loss is more gradual.
August 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This review explores the Ayurvedic perspective on hair loss, specifically Khalitya, by aligning its traditional pathogenesis with contemporary understanding of alopecia's causes, suggesting an integrative approach combining Ayurvedic and modern treatments could enhance management and provide personalized solutions for hair loss.
August 2025 in “Scientific Reports” This study found that the protein C4BPA may link insulin resistance and acne vulgaris by influencing lipid metabolism and inflammatory pathways, suggesting it as a potential mediator in the pathogenesis of both conditions.
August 2025 in “Dermatology and Therapy” This study conducted a meta-analysis of gene expression data from alopecia areata patients, identifying 5109 differentially expressed genes and highlighting enriched pathways like JAK-STAT signaling, providing insights into the disease's pathogenesis and potential treatment targets.
July 2025 in “Annals of Human Genetics” This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.
July 2025 in “Journal of Cutaneous Pathology” In this case report, a newborn with Conradi-Hünermann-Happle syndrome was diagnosed through early skin biopsy, which revealed unique histopathological features, including dystrophic calcifications, confirming a pathogenic variant in the EBP gene.
July 2025 in “Journal of Cosmetic Dermatology” In this study, authors present a case where a 26-year-old patient with alopecia areata experienced relapse after initially responding to Tofacitinib, mitigated by corticosteroids, highlighting challenges and potential insights into the treatment and pathogenesis of the condition.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this review, researchers examined the concentration of cortisol in scalp hair of individuals with alopecia areata to explore its relationship with disease variables, as cortisol in hair can indicate chronic stress, which may impact alopecia areata pathogenesis.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that anti-Ku-positive patients exhibit heterogeneous muscle features, primarily showing a myositis pattern with necrotizing fibers and vacuolar changes, and suggests autophagy may play a significant role in their pathogenesis.
May 2025 in “Journal of Clinical Medicine” This study suggests that women with alopecia have decreased microcirculation oscillations, which may imply neuroinflammation as a factor in the disease's pathogenesis.