January 2026 in “Quality in Sport” This review highlights that isotretinoin effectively treats acne by addressing its pathogenic mechanisms, although managing its teratogenic risk and side effects through structured monitoring is crucial for safe use.
November 2025 in “The Journal of Immunology” This study identified specific genes upregulated in skin γδ T cells involved in alopecia areata, with findings suggesting these cells contribute to disease pathogenesis through inflammatory and Th1 response mechanisms in mouse and possibly human skin.
December 2024 in “Pharmaceutics” This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.
November 2024 in “EMBO Molecular Medicine” This study used a mouse model to enhance understanding of alopecia pathogenesis and suggested a therapeutic strategy for managing inflammation in EGFR-inhibitor therapy-induced folliculitis and cicatricial alopecia.
October 2024 in “Our Dermatology Online” This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.
June 2023 in “World Journal of Biology Pharmacy and Health Sciences” This review outlines the complex factors involved in acne pathogenesis—including hormonal, genetic, and environmental influences—and describes current comprehensive management strategies, emphasizing both topical and systemic therapies, while also highlighting emerging treatment options and the significant psychological impact of acne.
June 2022 in “International Journal of Health Sciences (IJHS)” This review examines the role of certain proteins in the pathogenesis of polycystic ovary syndrome and reports no new results, emphasizing the potential for future diagnostic and therapeutic advancements.
January 2021 in “International Research Journal of Ayurveda & Yoga” This article explores the Ayurvedic perspective on PCOS pathogenesis and suggests that treatments focusing on balancing tridoshas and enhancing digestion may be effective, but it reports no new clinical results.
January 2016 in “International Journal of Dermatology and Venereology” This review discusses the association between aberrant DNA methylation and the pathogenesis of various inflammatory skin diseases but reports no new findings on the biological mechanisms involved.
November 2011 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review discusses the role of androgens and estrogens in acne pathogenesis and the potential use of oral contraceptives containing ethinyl estradiol and progestins to manage acne, but reports no new results.
May 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study suggests that decreased PPARgamma function may trigger the pathogenesis of lichen planopilaris, and PPARgamma-targeted therapy could be a potential treatment method.
41 citations
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December 2015 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the challenges and potential solutions in studying Demodex mites and their possible pathogenic role in human skin disorders but reports no new findings.
11 citations
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February 2021 in “Biomedicines” This review discusses the role of hair follicle bacterial colonization in immune responses and the pathogenesis of alopecia but reports no new clinical results.
10 citations
,
January 2009 in “Scientific Electronic Library Online (São Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Científico e Tecnológico)” This study found that Eclipta alba extracts exhibit significant antimicrobial activity against various human pathogens, including antibiotic-resistant strains, suggesting potential use in treating infectious diseases.
5 citations
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December 2022 in “Genes” This review discusses the host genetic factors influencing COVID-19 susceptibility and pathogenesis, highlighting genetic variations that affect viral entry and immune responses, but reports no new experimental results.
2 citations
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January 2024 in “Advances in Dermatology and Allergology” This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.
138 citations
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February 2007 in “European journal of cancer” This review discusses the classification, pathogenesis, and management of skin, hair, nail, and mucosal changes due to EGFR inhibitors, emphasizing the importance of informing patients to improve therapy compliance.
37 citations
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December 2007 in “International journal of clinical practice” This review discusses the definition, pathogenesis, diagnosis, and management of hirsutism and reports no new clinical results.
36 citations
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May 2025 in “Antioxidants” This study found that lipid peroxidation products play a clear role in the pathogenesis of skin diseases like psoriasis, vitiligo, and alopecia, but their role in diseases like melanoma and atopic dermatitis remains unclear.
35 citations
,
January 2014 in “BioMed Research International” This review examines the epidemiology, pathogenesis, clinical manifestations, and diagnosis of female pattern hair loss and reports no new results.
16 citations
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September 2015 in “International Journal of Molecular Sciences” In this study, a genetic analysis identified a pathogenic variant in the ALOXE3 gene associated with non-bullous congenital ichthyosiform erythroderma, and the patient's response to antifungal treatment highlights the risk of cutaneous fungal infections.
14 citations
,
February 2024 in “Biomolecules” This review explores the role of transient receptor potential vanilloid channels in the pathogenesis of osteoarthritis but reports no new clinical results.
10 citations
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January 2020 in “Advances in Dermatology and Allergology” This study suggests that the gene rs27647 polymorphism may play a role in the pathogenesis of severe acne vulgaris in post-adolescent male patients.
10 citations
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January 2013 in “Clinical and developmental immunology/Clinical & developmental immunology” This article is a special issue that reviews current research on the pathogenesis, diagnosis, and treatment of systemic autoimmune diseases, but it does not present new results.
9 citations
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February 2013 in “Hormone and Metabolic Research” This study reported that CYP21A2 heterozygous mutations do not significantly contribute to the pathogenesis of polycystic ovary syndrome.
6 citations
,
April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
3 citations
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October 2025 in “Biomedicines” This review of seborrheic dermatitis highlights the role of complex immunoinflammatory processes in its pathogenesis and discusses emerging treatments, such as PDE4 inhibitors, JAK inhibitors, and microbiome-targeted therapies, which may benefit patients with severe or treatment-resistant forms, according to the authors.
3 citations
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March 2022 in “Chinese Journal of Plastic and Reconstructive Surgery” This review discusses the potential role of androgen-related disorders in keloid pathogenesis and highlights the need for systemic treatments targeting sex hormones, but reports no new clinical results.
2 citations
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April 2017 in “Actas Dermo-Sifiliográficas” This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.