August 2022 in “Journal of Contemporary Medical Practice” This review discusses the possible roles of skin and intestinal microbiota in acne pathogenesis and covers related research on traditional Chinese medicine treatments, without reporting new clinical results.
April 2022 in “Health care of Tajikistan” This review discusses the etiology and pathogenesis of alopecia areata in children, highlighting the roles of heredity, immune factors, lipid peroxidation violations, microcirculation issues, and vitamin D deficiencies but reports no new clinical results.
March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology” This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.
September 2021 in “CRC Press eBooks” This article discusses the characteristics and pathogenesis of acne keloidalis nuchae among men with coarse curly hair, reviewing its association with factors like chronic inflammation and potential roles for metabolic syndrome and infection. It reports no new results.
August 2021 in “Benha Journal of Applied Sciences” This article reviews various hypotheses on the pathogenesis of vitiligo and aims to evaluate potential provoking factors, but presents no new clinical findings.
December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This mini review discusses insights into the pathogenesis of hidradenitis suppurativa, highlighting genetic mutations, autoinflammation, and the effectiveness of biologics, and introduces the concept of autoinflammatory keratinization disease, without reporting new clinical results.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identifies two previously unreported pathogenic RIPK4 gene variants, suggesting a functional link with cell adhesion molecules in ectodermal dysplasias.
November 2015 in “European Journal of Inflammation” This review discusses the potential pathogenic mechanisms of cicatricial alopecia and emphasizes the need for further research on treatment methods, but it reports no new clinical findings.
47 citations
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March 2022 in “Frontiers in cellular and infection microbiology” This review discusses the role of the skin microbiome in the pathogenesis of various skin disorders, such as atopic dermatitis and psoriasis, and reports no new clinical findings; it emphasizes potential therapeutic implications.
38 citations
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January 2017 in “PPAR Research” This review discusses the role of PPAR-γ in the pathogenesis of primary cicatricial alopecia, including its involvement in lichen planopilaris and treatment trials using PPAR-agonists, and reports no new clinical results.
8 citations
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September 2023 in “International Journal of Nanomedicine” In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.
3 citations
,
January 2017 in “PubMed” This report describes a case of inflammation and infection with specific pathogens in synthetic hair implants done by a non-medical professional, highlighting risks associated with the procedure.
3 citations
,
January 2016 This study found that wild and ancient maize genotypes host endophytes that can suppress fungal pathogens and aid in nutrient acquisition, supporting their potential role in plant growth and resilience.
1 citations
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July 2021 in “IntechOpen eBooks” This review discusses unspecific factors involved in the pathogenesis of skin diseases and potential ways cytokeratin changes might alleviate these conditions, but reports no new clinical results.
November 2025 in “Frontiers in Immunology” This review discusses the role of immune cells in the pathogenesis of alopecia areata and highlights emerging immunomodulatory strategies and novel therapeutic targets aimed at offering more effective and durable treatments for this autoimmune hair loss disorder.
102 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.
49 citations
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August 2022 in “Frontiers in Immunology” This paper discusses the evolving understanding of psoriasis pathogenesis with no new clinical findings; the authors highlight the role of T-cell plasticity and regulatory cells, calling for further clinical applications using single-cell technologies.
46 citations
,
April 2008 in “Archives of Dermatological Research” This study found that substance P may be involved in the pathogenesis of acne by increasing the expression of certain cytokines and receptors in cultured sebocytes.
45 citations
,
May 2024 in “International Journal of Molecular Sciences” This manuscript reviews the latest understanding of alopecia areata's pathogenesis, highlighting the roles of genetic, immunological, and environmental factors, with a focus on immune responses involving IFN-γ and cytotoxic CD8+ T-cells as key contributors to hair follicle inflammation and function disruption without follicle destruction.
45 citations
,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” This study found that plasmacytoid dendritic cells are central to the pathogenesis of alopecia areata, suggesting they may help differentiate it from trichotillomania and androgenetic alopecia.
27 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.
24 citations
,
September 2011 in “Autoimmunity” This review discusses the role of natural killer cells in the pathogenesis of blistering diseases and proposes further research on their interaction with the skin, reporting no new clinical results.
24 citations
,
January 2008 in “KARGER eBooks” This review discusses recent advances in understanding the pathogenesis of autoimmune alopecia areata and reports no new clinical results; it highlights potential for developing more effective treatments.
21 citations
,
July 2014 in “Clinics in Dermatology” This review examines the role of hormones in acne pathogenesis, the use of hormonal therapies for treatment, and the importance of contraceptive counseling during isotretinoin therapy, but reports no new clinical results.
15 citations
,
January 2023 in “Antioxidants” This review discusses oxidative stress in alopecia areata pathogenesis and potential treatment strategies, reporting no new clinical results but suggesting biomarkers for oxidative stress and discussing JAK inhibitors as promising options.
8 citations
,
March 2023 in “International Wound Journal” The researchers reported that several m6A-related genes, particularly IGF2BP3, were differentially expressed in keloid tissue compared to normal skin, indicating potential targets for understanding keloid pathogenesis and treatment.
7 citations
,
May 1993 in “Journal of the European Academy of Dermatology and Venereology” This review examines the role of cell adhesion molecules in the pathogenesis of various inflammatory and neoplastic skin diseases, suggesting their potential utility in diagnosis and treatment without presenting new clinical results.
4 citations
,
April 2008 in “Experimental Dermatology” This review hypothesizes that nicotine plays a crucial role in the pathogenesis of hidradenitis suppurativa by promoting inflammation and microbial growth, suggesting that anticholinergic agents might be a potential treatment strategy, but reports no new clinical findings.
2 citations
,
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that host androgens like testosterone promote Staphylococcus aureus pathogenesis and skin infections by activating the agr quorum sensing system, revealing a mechanism for sex-dependent differences in these infections.
2 citations
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July 2022 in “Cutis” This review discusses the role of the mTORC1 pathway in acne pathogenesis in relation to diet and reports no new results.