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    Glossary Paclitaxel

    chemotherapy drug that inhibits cancer cell division

    Paclitaxel, also known by the brand name Taxol, is a chemotherapy medication used to treat various types of cancer, including breast, ovarian, and lung cancer. It works by inhibiting cell division, which prevents cancer cells from growing and spreading. This drug can cause side effects such as hair loss (alopecia), as it affects rapidly dividing cells, including those in hair follicles.

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    Research 30 of 598

    1. Irreversible and severe alopecia following docetaxel or paclitaxel cytotoxic therapy for breast cancer 2009 · 61 citations
    2. Paclitaxel-loaded star-shaped copolymer nanoparticles for enhanced malignant melanoma chemotherapy against multidrug resistance Drug Design Development and Therapy · 2017 · 43 citations
    3. Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy Scientific Reports · 2017 · 28 citations
    4. Cardioprotective effect of royal jelly on paclitaxel-induced cardio-toxicity in rats. PubMed · 2016 · 24 citations
    5. First-line therapy with gemcitabine and paclitaxel in locally, recurrent or metastatic breast cancer: A phase II study BMC Cancer · 2005 · 22 citations
    6. Ayurveda-based Botanicals as Therapeutic Adjuvants in Paclitaxel-induced Myelosuppression Frontiers in Pharmacology · 2022 · 12 citations
    7. Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-induced Cytotoxicity Journal of Cancer · 2022 · 11 citations
    8. Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer Journal of Clinical Oncology · 2022 · 9 citations
    9. Noyes-Whitney Dissolution Model-Based pH-Sensitive Slow Release of Paclitaxel (Taxol) from Human Hair-Derived Keratin Microparticle Carriers BioMed research international · 2021 · 9 citations
    10. Taxane-induced alopecia: A historical review of patients with ovarian or breast cancer treated with with paclitaxel, docetaxel or paclitaxel poliglumex Journal of Clinical Oncology · 2005 · 5 citations
    11. XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity Cell division · 2020 · 4 citations
    12. Epigallocatechin-3-gallate inhibits paclitaxel-induced apoptosis through the alteration of microRNA expression in human dermal papilla cells Biomedical dermatology · 2018 · 3 citations
    13. Absence of chemotherapy-induced alopecia with paclitaxel in a case of hypothyroidism: case report Annals of Oncology · 2003 · 3 citations
    14. Cemotherapi Induce Alopecia Due Carboplatin-Paclitaxel Regiment International Journal of Advanced Multidisciplinary Research and Studies · 2024 · 1 citations
    15. Melatonin protects K15+ human hair follicle stem cells and hair matrix keratinocytes against paclitaxel-induced damage ex vivo Journal of Investigative Dermatology · 2023 · 1 citations
    16. Perspective Chapter: Appraisal of Paclitaxel (Taxol) Pros and Cons in the Management of Cancer – Prospects in Drug Repurposing IntechOpen eBooks · 2023 · 1 citations
    17. 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia Journal of Investigative Dermatology · 2022 · 1 citations
    18. Alopecia/hair loss in all patients treated with trastuzumab and paclitaxel: myth or reality? Annals of Oncology · 2017 · 1 citations
    19. Paclitaxel/Platinum combination regimen and alopecia 2012 · 1 citations
    20. Disruption of microtubules with low intensity ultrasound rescues hair follicle damage by paclitaxel in mouse models Nature Communications · 2026
    21. Subacute cutaneous lupus erythematosus in a patient of pancreatic cancer secondary to novel albumin-bound paclitaxel chemotherapy Indian Journal of Skin Allergy · 2023
    22. ISID1403 - Melatonin protects K15+ human hair follicle stem cells against paclitaxel-induced damage ex vivo 2023
    23. 1403 Melatonin protects K15+ human hair follicle stem cells against paclitaxel-induced damage ex vivo Journal of Investigative Dermatology · 2023
    24. EXPERIENCE OF A PRIVATE HOSPITAL IN THE FEDERAL DISTRICT IN CRYOTHERAPY WITH A HYPOTHERMAL CAP FOR PATIENTS USING PACLITAXEL 80 MG/M² WEEKLY FOR 12 WEEKS Mastology · 2021
    25. Preclinical Development and Phase I Study of ZSYY001, a Polymeric Micellar Paclitaxel for Advanced Solid Tumor Cancer Medicine · 2025 · 6 citations
    26. Phase II trial of paclitaxel poliglumex (CT-2103) in pre- and post-menopausal women on hormonal replacement therapy (HRT) with non-small cell lung cancer (NSCLC). Journal of Clinical Oncology · 2011 · 2 citations
    27. Efficacy of albumin-bound paclitaxel combined with nedaplatin in neoadjuvant therapy for esophageal squamous cell carcinoma: A single-center retrospective observational study Medicine · 2023 · 1 citations
    28. A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable Stage III Non-Small Cell Lung Cancer Recent Patents on Anti-Cancer Drug Discovery · 2025
    29. Observational Study of Paclitaxel-Carboplatin versus Pemetrexed-Carboplatin for Advanced Pulmonary Adenocarcinoma at Single-Centre in Indonesia eJournal Kedokteran Indonesia · 2022
    30. S-l Combined with Paclitaxel as Second-line Chemotherapy for Advanced Gastric Cancer Zhongguo quanke yixue · 2012