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    Glossary p38 MAPK pathway

    regulates cellular responses to stress and inflammation

    The p38 MAPK pathway, also known as the p38 mitogen-activated protein kinase pathway, is a signaling pathway in cells that responds to stress stimuli, such as inflammation and UV radiation. It plays a crucial role in regulating cellular processes like inflammation, cell growth, and apoptosis (programmed cell death). This pathway is significant in various diseases, including cancer and autoimmune disorders, and is a target for therapeutic interventions.

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    Research 30 of 984

    1. Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways Frontiers in Microbiology · 2021 · 30 citations
    2. Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway Drug Design Development and Therapy · 2025
    3. Sinapic Acid Promotes Browning of 3T3‐L1 Adipocytes via p38 MAPK/CREB Pathway BioMed Research International · 2020 · 29 citations
    4. Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways Journal of Nanobiotechnology · 2025 · 9 citations
    5. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    6. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    7. Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo Aging · 2022 · 6 citations
    8. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes edoc (University of Basel) · 2014
    9. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    10. Abstract 2962: Chemotherapy induced senescence drives peripheral neuropathy Cancer Research · 2024
    11. Sesamin alleviates androgenetic alopecia by targeting the AR MAPK Wnt axis Scientific Reports · 2026
    12. Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons Chemosphere · 2017 · 10 citations
    13. Targeting the Thy-1 mechanotransduction regulator rescues regenerative wound healing and induces hair follicle neogenesis under high tension Cellular and Molecular Life Sciences · 2026
    14. The potential application of natural products in cutaneous wound healing: A review of preclinical evidence Frontiers in Pharmacology · 2022 · 45 citations
    15. Microenvironment-Responsive Recombinant Collagen XVII-Based Composite Microneedles for the Treatment of Androgenetic Alopecia Acta Biomaterialia · 2025
    16. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    17. Il-10 family members as novel responders to genotoxic stress ScholarlyCommons (University of Pennsylvania) · 2015
    18. Protective Effect of Iris germanica L. Rhizome-Derived Exosome against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes Applied sciences · 2023
    19. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020 · 25 citations
    20. Docosahexaenoic acid-acylated astaxanthin esters alleviate cisplatin- induced acute kidney injury by modulating the ferroptosis-related GPX4/xCT signaling pathway and reducing oxidative stress Food Science and Human Wellness · 2026
    21. Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways International Journal of Molecular Sciences · 2018 · 14 citations
    22. <i>Malva verticillata</i>seed extracts upregulate the Wnt pathway in human dermal papilla cells International Journal of Cosmetic Science · 2015 · 25 citations
    23. Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment Journal of Ethnopharmacology · 2024
    24. Network Pharmacology Reveals Curcuma aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia Biology · 2024
    25. In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells Frontiers in Pharmacology · 2024
    26. LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway Stem cell research & therapy · 2016 · 53 citations
    27. Anticancer Effects of Broccoli Sprout Extract and Sulforaphane Through ROS-Induced MAPK Pathway in Breast Cancer Cells and Xenografts Antioxidants · 2026
    28. Regulatory Mechanisms of Natural Active Ingredients and Compounds on Keratinocytes and Fibroblasts in Mitigating Skin Photoaging Clinical Cosmetic and Investigational Dermatology · 2024 · 10 citations
    29. Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways International Journal of Molecular Sciences · 2024 · 3 citations
    30. Combined Physicochemical and Transcriptomic Analyses Reveal the Effect of Black Wolfberry Ferment on Alopecia Journal of Food and Nutrition Research · 2025