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    Did you mean Human Outer Root Sheath Cells?
    Glossary Human Outer Root Sheath Cells

    cells in hair follicle's outer layer aiding growth and regeneration

    Human Outer Root Sheath Cells are a type of cell found in the outer layer of the hair follicle. These cells play a crucial role in the growth and regeneration of hair, as they provide structural support and house stem cells that can differentiate into various cell types needed for hair production.

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    1. Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro Journal of dermatological science · 2009 · 51 citations
    2. The chemotactic effect of a dermal papilla cell-derived factor on outer root sheath cells Journal of Dermatological Science · 2001 · 47 citations
    3. Wnt/β‐catenin and ERK pathway activation: A possible mechanism of photobiomodulation therapy with light‐emitting diodes that regulate the proliferation of human outer root sheath cells Lasers in Surgery and Medicine · 2017 · 43 citations
    4. Manipulation of outer root sheath cell survival perturbs the hair-growth cycle The EMBO Journal · 1999 · 37 citations
    5. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    6. Organotypic culture of outer root sheath cells from human hair follicles using a new culture device In Vitro Cellular & Developmental Biology - Plant · 1987 · 35 citations
    7. Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells Biochemical and Biophysical Research Communications · 2007 · 34 citations
    8. VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway Molecular Biology Reports · 2012 · 23 citations
    9. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    10. miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020 · 18 citations
    11. Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells Journal of Dermatological Science · 1994 · 16 citations
    12. Novel ALK5 inhibitor TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles Pharmacological Reports · 2017 · 14 citations
    13. FORMATION OF A REGULAR NEO-EPIDERMIS BY CULTURED HUMAN OUTER ROOT SHEATH CELLS GRAFTED ON NUDE MICE Transplantation · 1995 · 14 citations
    14. Interferon β Secreted from Human Hair Dermal Papilla Cells Inhibits the Growth of Outer Root Sheath Cells Cultured in Vitro Biochemical and biophysical research communications · 2002 · 13 citations
    15. Effects of 1?,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsoriatic drugs Archives of dermatological research · 1993 · 10 citations
    16. Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cell Tissue Engineering and Regenerative Medicine · 2020 · 9 citations
    17. A novel monoclonal antibody to the outer root sheath cells Journal of Dermatological Science · 1994 · 3 citations
    18. A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells 1989 · 2 citations
    19. Nerve growth factor regulates the proliferation of cashmere goat outer root sheath cells through the activation of cAMP-binding protein Small ruminant research · 2019 · 1 citations
    20. Effect of Minoxidil Sulfate on the Growth of Human Anagen Hair Follicles Grown in Collagen Gels, and on the Colony Growth of Human Cultured Outer Root Sheath Cells in vitro. The Nishinihon Journal of Dermatology · 1992 · 1 citations
    21. Outer root sheath cells secrete oxytocin for hair growth promotion and stem cell proliferation Journal of Bioscience and Bioengineering · 2026
    22. 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase Biological and Pharmaceutical Bulletin · 2024
    23. 1332 Janus kinase inhibitor increases hair growth by increasing beta-catenin activity in outer root sheath cells 2023
    24. P140 Light-emitting diode light regulates the proliferation of human outer root sheath cells via Wnt/β -catenin and ERK pathway 프로그램북(구 초록집) · 2016
    25. Epidermal growth factor induced apoptosis in the outer root sheath cells of anagen hair and changed the hair cycle to the catagen phase Kitasato medical journal · 2004
    26. Role of the Wnt/β-Catenin Signaling Pathway in Mediating Outer Root Sheath Stem Cells to Promote Hair Follicle Regeneration and Skin Wound Healing in Mice Cells · 2026
    27. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    28. Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes Veterinary Dermatology · 2019 · 12 citations
    29. Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes Cell and Tissue Research · 1994 · 36 citations
    30. [An immunohistochemical study on cell differentiation in the outer root sheath of the normal human anagen hair follicles with antikeratin monoclonal antibodies]. PubMed · 1990 · 6 citations