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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain drugs that block specific enzymes can help treat prostate diseases.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Endocrine therapies for cancer significantly increase the risk of hair loss.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.