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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Reproductive gynecologists are the main referrers for male infertility evaluations in North America.

Certain gene variations are not a major cause of male infertility in Nigerian men.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

Finasteride causes lasting fertility decrease in rats.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.