8 citations
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October 2016 in “Actas Dermo-Sifiliográficas” This study found that men with frontal fibrosing alopecia exhibited more frequent facial papules, androgenetic alopecia, and body hair loss compared to women with the condition, and were generally older.
7 citations
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January 2018 in “Journal of Tissue Viability” This case report describes an 80-year-old patient whose scalp wound healed by secondary intention, with unexpected hair regrowth observed at 180 days, suggesting hair neogenesis is possible even in older adults.
6 citations
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May 2024 in “JAAD Case Reports” This study highlights that topical ruxolitinib cream is FDA-approved for mild to moderate atopic dermatitis and nonsegmental vitiligo in patients aged 12 and older, but its use in other skin conditions like frontal fibrosing alopecia remains under-researched and needs further exploration in clinical practice.
6 citations
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March 2024 in “SKIN The Journal of Cutaneous Medicine” In this ongoing phase 3 study, ritlecitinib demonstrated sustained efficacy up to 24 months in patients aged 12 or older with alopecia areata, showing increased response rates with or without an initial loading dose and supporting its long-term use.
6 citations
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February 2022 in “The journal of neuroscience/The Journal of neuroscience” This study observed that deleting PTEN in mouse facial motoneurons enhanced peripheral axon regeneration but also led to physiological changes and potential hyperplasia in older mice.
6 citations
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July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that HAP stem cells from the whiskers of young mice near the ear differentiated into heart-muscle cells more efficiently than those from older mice or other whisker locations.
5 citations
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April 2024 in “Animals” This study found that in cashmere goats aged 2 to 7 years, younger goats (2-4 years) produced more cashmere and had a higher population of active secondary hair follicles than older goats (5-7 years), with the latter showing greater oxidative stress.
5 citations
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July 2022 in “International Journal of Trichology” This retrospective study found that hair loss occurred in some isotretinoin patients, with those experiencing hair loss being older and having longer treatment durations and higher doses compared to controls.
5 citations
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August 2021 in “Frontiers in Cell and Developmental Biology” This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.
4 citations
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November 2023 in “SKIN The Journal of Cutaneous Medicine” In this study, ritlecitinib, an oral JAK3/TEC inhibitor, was evaluated for safety in patients aged 12 and older with alopecia areata across four clinical trials up to 36 months, showing a safety profile with reported adverse events and lab abnormalities summarized per dosing groups.
4 citations
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August 2020 in “Journal of The American Academy of Dermatology” This review critiques a study on androgenetic alopecia in hospitalized COVID-19 patients, highlighting analytical inaccuracies and suggesting that the condition's prevalence may relate to older age rather than COVID-19 infection.
4 citations
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August 2018 in “Journal of Cosmetic Dermatology” This study observed that actual harvested grafts in hair transplantation yielded more 1-hair follicular units and fewer 3-hair follicular units than originally estimated, with older age and multiple procedures limiting donor scalp harvesting.
3 citations
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November 2020 in “Ciencia Tecnología y Salud” This review describes the signs, symptoms, and complications of COVID-19, noting that symptoms often overlap with common and non-specific features, especially in older adults and in different stages of illness.
2 citations
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April 2023 in “BMC endocrine disorders” In this study, a significant positive correlation between clinical hyperandrogenism and free androgen index was found in younger women with PCOS, but not in older women.
2 citations
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June 2016 in “International journal of experimental pathology” This study found that expression of GDNF and GFR α-1 proteins in human skin decreases with age, particularly in the epidermis, suggesting that their signaling pathways may be altered as people grow older.
2 citations
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July 1999 in “Liver transplantation and surgery” Liver transplant can lead to neurological, pulmonary, cardiovascular, and renal complications, with older patients facing higher risks.
1 citations
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December 2025 in “Photodermatology Photoimmunology & Photomedicine” This study found that early initiation of phototherapy is an effective treatment strategy for certain subtypes of AA, particularly in older patients and those with a shorter disease duration.
1 citations
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April 2025 in “Clinical Cosmetic and Investigational Dermatology” This report describes a rare case of porokeratotic eccrine ostial and dermal duct nevus in a 64-year-old woman, successfully treated with CO₂ laser, highlighting its potential occurrence in older adults.
1 citations
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August 2024 in “PubMed” This study demonstrated that carboxytherapy significantly increased epidermal and dermal thickness, improved collagen and elastin organization, and enhanced expression of TGF-β1 and VEGF in older skin.
1 citations
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May 2021 in “Problemy e̊ndokrinologii” This study found that in men, elevated androgen levels can occur at any age, with older men potentially exhibiting increased total testosterone due to higher levels of SHBG, and younger men showing various clinical manifestations like acne and alopecia.
1 citations
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January 2021 in “International journal of pharmaceutical research” This study found that reduced levels of ferritin, TSH, and hemoglobin in young women and lower TSH, vitamin B12, and vitamin D in older women are associated with chronic diffuse hair loss.
1 citations
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September 2019 in “Pomeranian Journal of Life Sciences” This study found that Demodex infestation was present in 21% of healthy volunteers, with higher rates in older individuals and more common in PUM personnel than students.
1 citations
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October 2016 in “Journal of medical science and clinical research” This study found that younger male patients with androgenic alopecia experienced greater stigmatization and emotional instability but maintained higher self-assuredness and better overall quality of life compared to older patients.
1 citations
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January 2004 in “The Internet Journal of Geriatrics and Gerontology” This review discusses the clinical aspects, diagnosis, and treatment options for androgenetic alopecia, ultimately calling for further research, particularly regarding older populations and possible health risks.
June 2026 in “Journal of Orthopaedic Science and Research” In this case study, a 65-year-old man with a complete ACL rupture showed MRI-documented re-continuity and restoration of function after delayed conservative treatment with platelet-rich plasma, highlighting the potential for recovery in older patients and supporting further research into patient selection and treatment protocols.
June 2026 in “Annals of Middle Eastern Medicine” This study found significant gaps in knowledge about PCOS and related health practices among women in southwestern Saudi Arabia, with older age and lower education predicting inadequate understanding.
April 2026 in “Journal of Clinical Medicine” In this study, men with previous finasteride use reported more severe sexual and psychological symptoms with greater cumulative exposure and older age, highlighting a need for further research on risk factors and long-term impacts.
March 2026 in “American Journal of Clinical Dermatology” In this study, ritlecitinib 50 mg produced clinically meaningful improvements in scalp hair regrowth over three years for patients aged 12 and older with severe alopecia areata, with 65.1% showing substantial hair regrowth and 31.2% achieving complete regrowth, while also maintaining a consistent safety profile.
March 2026 in “PubMed Central” This study reports that the prevalence of female pattern hair loss increases with age, affecting 12% of women by age 29, 25% by age 50, and 41% to 50% by age 70 and older, with risk factors including genetics and certain endocrinological conditions.
This study explored how men's perceived height and androgenetic alopecia affect social and personality impressions, reporting a potential "attractiveness malus" but noting limitations due to an older dataset, selective sample, and cultural homogeneity among raters.