July 2022 in “Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)” This study observed that in COVID-19 patients at Zahirah General Hospital, older men with diabetes were more prone to severe symptoms and had lower lymphocyte levels.
December 2021 in “Innovation in aging” This study found that frailty independently raises the risk of clinical BPH progression and serious adverse events in older men, suggesting that shared decision-making is essential when considering medical therapy for frail patients.
October 2021 in “Journal of Investigative Dermatology” This study found that reconstructed human epidermis from infant skin is more susceptible to UV damage than that from older children, with notable changes in skin cell characteristics during the early years of life.
September 2021 in “Conference Proceedings” This study observed that hyperandrogenism in men manifests with varying symptoms, where older men may have high total testosterone due to increased SHBG without elevated free testosterone, while younger men often show signs like acne and alopecia with elevated DHT or testosterone.
May 2019 in “Australasian Journal of Dermatology” The document updated knowledge on skin disorders, focusing on unusual moles in older adults, the progression from moles to melanoma, and evolving hair loss treatments.
October 2015 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study observed smaller reductions in PSA levels in men under 40 taking finasteride 1mg/day compared to older age groups, without changes in testosterone levels.
June 2014 in “British Journal of Dermatology” Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.
February 2006 in “Journal of The American Academy of Dermatology” Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.
August 2003 in “Oncology Times” This article discusses the considerations and challenges surrounding a proposed large-scale trial on testosterone-replacement therapy in older men and reports no new results.
January 1994 in “Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics” In this study, both VEPA and ML-Y1 treatment regimens for older patients with non-Hodgkin's lymphoma showed similar response and survival rates, but neither was sufficient, indicating the need for a more effective approach.
July 2021 in “JOURNAL OF THE MEDICAL ASSOCTATION OF THAILAND” In this study, young Thai men with androgenetic alopecia reported poorer quality of life compared to older men, as indicated by higher DLQI scores.
March 2018 in “Nepal journal of dermatology, venereology & leprology” This study observed no association between androgenetic alopecia and benign prostatic hyperplasia in men aged 20 and older, although a positive family history was linked to early onset of hair loss.
71 citations
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December 2010 in “Preventive Veterinary Medicine” This study found that Microsporum canis was the most prevalent dermatophyte in dogs and cats in Western Turkey, with younger animals more frequently infected than older ones.
48 citations
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May 2015 in “PLOS ONE” This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.
44 citations
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July 2011 in “Dermatologic Therapy” This study found that finasteride 1 mg was effective in improving androgenetic alopecia over 10 years in men, particularly those older than 30, with some reporting beneficial results even after 5 years.
29 citations
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March 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that the severity, duration, and relapse rate of alopecia areata decreased with older age at onset, while relapses mostly occurred early and declined over time.
25 citations
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December 1991 in “The Journal of Dermatology” This study found that cyclosporin A treatment in young nude mice induced dose-dependent hair growth, which stopped after treatment cessation, but did not result in hair growth in older mice.
23 citations
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October 2024 in “British Journal of Dermatology” In this study, ritlecitinib showed sustained effectiveness and a favorable safety profile in treating alopecia areata in patients aged 12 and older over 24 months, with improvements observed in hair and eyebrow regrowth and patient satisfaction.
23 citations
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November 2013 in “Lupus” This study found that the quality of life for Japanese lupus erythematosus patients with skin manifestations improved after treatment, though female gender and older age were associated with poorer outcomes in certain quality of life domains.
23 citations
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August 2005 in “Expert opinion on pharmacotherapy” This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.
21 citations
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July 2014 in “British Journal of Dermatology” In this study, hair loss in Japanese men with androgenetic alopecia was found to be primarily due to hair follicle miniaturization rather than hair shedding, particularly in those aged 25 and older.
14 citations
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December 2001 in “Journal of autoimmunity” This study found that immunity to self-prion peptides could be induced in Lewis rats, but in older rats, it was associated with severe skin inflammation and hair loss.
13 citations
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February 2018 in “Dermatologic Therapy” This study found that 65.2% of female pattern hair loss patients showed significant hair growth improvement with a daily dosage of 2.5 mg finasteride, with better outcomes in patients with lower initial Ludwig scores and older age at onset.
12 citations
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November 2021 in “Journal of Clinical Medicine” This study reported that 70.1% of kidney transplant recipients experienced persistent symptoms of post-COVID-19 syndrome six months after infection, with older patients and those with more comorbidities being more affected.
11 citations
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April 1982 in “Journal of the Forensic Science Society” This study found that specific enzymes could be detected in fresh hair sheath cells, with most remaining detectable in older cells, except for Adenylate kinase and Esterase D.
10 citations
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February 2022 in “Epidemiologia” This study reported that about one-third of post-COVID-19 patients experienced long-term symptoms, with women, older individuals, smokers, and those with specific blood groups at higher risk for complications.
10 citations
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December 2010 in “British Journal of Dermatology” This study reports two distinct patterns of hair changes in postmenopausal women, linking diffuse generalized scalp hair loss to older age and frontal hair loss to higher facial hair scores and younger age.
10 citations
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May 2008 in “Dermatologic Surgery” This study observed that densely packed follicular unit grafts using the lateral slit technique have high growth rates, even at 72 grafts/cm², contradicting previous findings with older methods.
9 citations
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September 2019 in “Clinical Cosmetic and Investigational Dermatology” In this article, the authors reported that calcipotriol/betamethasone dipropionate aerosol foam significantly improved scalp psoriasis symptoms in three patients by reducing itching and improving flaky patches within a four-week treatment period, confirming its efficacy and enhanced skin penetration compared to older formulations.
8 citations
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April 2021 in “Medical journal of the Islamic Republic of Iran” This study found that a short course of finasteride improved oxygen saturation but had no significant impact on mortality rate or length of hospital stay in older male COVID-19 pneumonia patients.