January 2025 in “Mansoura Medical Journal” In this animal study, researchers observed that both aging and lower androgen levels in male albino rats led to significant structural changes in meibomian glands, including reduced acinar cell size, diminished meibum secretion, and increased collagen deposition.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified distinct and diverse fibroblast populations in female scalp cells that lose their signature and identity with age, highlighting significant age-related changes, such as increased fibrosis, DNA damage, and senescence, which may affect scalp dermal support for healthy hair follicles.
November 2022 in “Innovation in aging” This study reports that hair cortisol measurement in older Puerto Rican adults found a significant portion had non-detectable cortisol levels, especially among black participants, influencing exclusion rates in such populations.
April 2018 in “Journal of Investigative Dermatology” This study reports that in aged mice, hair follicle dermal stem cells exhibit diminished self-renewal and preferential differentiation into dermal sheath cells, contributing to age-related hair loss.
This study identified several age-related changes in gene expression associated with the extracellular matrix of scalp dermal fibroblasts, which may impact hair follicle maintenance in women over 40.
April 2018 in “Journal of Investigative Dermatology” This study observed that, contrary to common belief, aged Balb/C mice showed better wound healing than younger mice despite greater weight loss, possibly due to increased T regulatory cells.
April 2011 in “The Journal of Urology” This study concluded that finasteride is most cost-effective for prostate cancer chemoprevention when started at age 65 and continued until age 80.
December 2023 in “Y Dược học” In this study, researchers found that 11.5% of older outpatients in Vietnam experienced post-COVID-19 hair loss; women, those single or divorced, and individuals with prior COVID-19 hospitalizations were more likely to report hair loss.
June 2026 in “Comprehensive Psychoneuroendocrinology” In this study, researchers observed a curvilinear relationship between loneliness and hair cortisol concentration among older adults at elevated cardiovascular risk, with cortisol levels higher at low-to-moderate loneliness and lower at higher loneliness, though results were sensitive to some data exclusions.
26 citations
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June 2022 in “Stem Cell Research & Therapy” This study found that Tideglusib enhances wound healing in aged rats by activating the PI3K/Akt pathway, suggesting its potential for medical and cosmetic applications targeting age-related skin changes.
17 citations
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November 2010 in “Perspectives on Psychological Science” This study found that age-related cues, such as perceived appearance, clothing, and family structure, may influence health outcomes and longevity in different ways.
10 citations
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September 2020 in “Journal of the American Geriatrics Society” This study found that a natural language processing system outperformed ICD code-based strategies in accurately identifying fall-related emergency department visits among older adults.
5 citations
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January 2007 in “Annals of Internal Medicine” Folic acid might help with age-related hearing loss.
This study found that perceptions of scalp micropigmentation and awareness of its side effects vary significantly by gender and age, influencing attitudes and intentions toward the procedure.
October 2014 in “Aktuelle Dermatologie” This study reports that elderly men with baldness and comorbid conditions experienced persistent scalp erosions following topical treatment with imiquimod or diclofenac, suggesting alternative therapies should be considered for this group.
8 citations
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January 2018 in “Journal of cosmetic dermatology” This study found that conditioner agents reduced the damage caused by oxidative hair dye, specifically improving protein retention and combability in treated Caucasian hair.
November 2024 in “International Society of Hair Restoration Surgery” This study investigated adverse events from low-dose systemic minoxidil in an older population with hair loss and found that 19% experienced mainly facial and body hypertrichosis, managed with interventions like dose reduction and diuretics; no serious adverse events occurred.
417 citations
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February 2004 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy increased bone mineral density in older men with low testosterone, and combining it with finasteride may reduce prostate enlargement associated with testosterone treatment.
119 citations
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August 2010 in “Journal of Investigative Dermatology” This study reports that 11β-HSD1 activity in human skin increases with age and photoexposure, potentially contributing to skin aging and the effects of glucocorticoids.
34 citations
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December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” This review discusses the potential of DHEAS and testosterone treatments to increase muscle mass in older men with sarcopenia, while effects on muscle function and physical performance remain unclear, and calls for further research on optimized approaches.
1 citations
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October 2023 in “The Journal of nutrition, health & aging” In this study, hair levels of zinc and chromium were associated with a reduced likelihood of age-related cognitive decline in centenarians and oldest-old adults, suggesting further research is needed on these elements' potential role in cognitive health among the elderly.
February 2025 in “Journal of Women & Aging” This study identified a significant trend among Black women towards less frequent use of complex hairstyles and salon visits over 30 years, while managing grey hair became a key element of personal and social identity.
September 2023 in “Frontiers in cell and developmental biology” This study found that a catalytically active version of Vav2 significantly altered gene expression patterns in hair follicle stem cells in mice, with these changes varying over the animals' lifespans.
This article reviews the nutritional needs and challenges for the elderly, emphasizing the benefits of antioxidants and healthy fats for immune support and overall health, but presents no new clinical results.
October 2010 in “Journal of Men's Health” This study found that adolescent men in Ireland are more likely to prefer keeping a baby over abortion in a hypothetical unplanned pregnancy, influenced by their anticipated regret and perceived familial attitudes.
August 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study reported that administering a supraphysiological dose of testosterone for one year resulted in minor cognitive benefits and decreased depressive symptoms in older hypogonadal men, but major cognitive improvements were not observed.
March 2026 in “SKIN The Journal of Cutaneous Medicine” This study found that ritlecitinib was well tolerated in children aged 6 to under 12 years with severe alopecia areata, with ongoing trials examining its efficacy and safety over a 24-week period and in long-term use up to 36 months.
May 2020 in “Journal of Asian Medical Students' Association” This study concluded that psychological well-being and self-image among Filipino males with androgenetic alopecia may be influenced by age, education level, and disease severity.
34 citations
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September 2013 in “Urology” Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
7 citations
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May 2008 in “PubMed” This study found that patients treated with dutasteride were significantly less likely to experience acute urinary retention and prostate-related surgeries compared to those treated with finasteride.