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This source reports that clascoterone cream, a topical androgen receptor inhibitor, has shown effectiveness in treating facial acne vulgaris in patients 12 and older, with clinical trials indicating a favorable safety profile compared to systemic treatments, and potential for broader dermatological applications.

This study found that in patients undergoing allogeneic hematopoietic stem-cell transplantation, older age significantly increases the risk of hemorrhagic cystitis, especially in males, who are also affected by prostatic hyperplasia.

In this study, baricitinib treatment over an average of 18.5 months resulted in a 72% reduction in alopecia severity scores among patients aged 65 or older, with mild adverse effects and no severe complications reported.

In this study, researchers found that melanoma risk factors and characteristics vary with age, noting distinct differences in younger, middle-aged, and older patients, with strong correlations in the oldest group.

This article highlights the complexity of diagnosing hyponatremia in older adults, emphasizing the need to evaluate urinary tract obstruction, medication effects, and age-related changes rather than relying solely on spot urinary values.

In this study, a significant positive correlation between clinical hyperandrogenism and free androgen index was found in younger women with PCOS, but not in older women.

This study found that finasteride 1 mg was effective in improving androgenetic alopecia over 10 years in men, particularly those older than 30, with some reporting beneficial results even after 5 years.

The authors concluded that specific comorbidities and complications increase the risk of severe COVID-19 and impede patient recovery, making them critical factors to control in order to lessen the disease's adverse effects.

This study found that reduced levels of ferritin, TSH, and hemoglobin in young women and lower TSH, vitamin B12, and vitamin D in older women are associated with chronic diffuse hair loss.

Most older adults experience pattern hair loss due to shrinking hair follicles, with men and women showing different balding patterns.

This study found that women with negative or mixed feelings about Botox and facial fillers reported diverse and sometimes persistent physical and psychological impacts, feeling commodified, fractured, abandoned, reflective, and transformed.

This study found that older males and those with previous skin cancer or a history of outdoor work had an increased risk of skin cancer or its precursors.

This study found that in older adults, skin cancer was more prevalent among males and those with a history of skin cancer or outdoor work.

This study suggests that supplementing with a cell-free fat extract might enhance embryo development and improve clinical outcomes in older women experiencing in vitro fertilization failure.

This article discusses the increasing use of lifestyle drugs by healthy individuals to alter appearance or slow aging and emphasizes the need for doctors to consider side effects and contraindications, but it reports no new clinical findings.

Older men with lower levels of available testosterone are more likely to be frail.

Older adults may experience painful finger pitting due to nerve changes in aging skin, and treatments can help reduce symptoms.

This study examined the incidence of hyperkalemia in women over 65 with female pattern hair loss and spironolactone use, but the findings on risk remain unclear.

This study found that among MtF transgender individuals, those with early-onset gender dysphoria exhibited differences in age at surgery, sexual orientation, and sexual activity compared to those with later-onset dysphoria.

This study highlights age and sex as key factors influencing scalp parameters, thereby affecting hair health and suggesting they should be considered in developing hair care strategies.

This study investigated age-related changes in female scalp dermal fibroblasts, finding alterations in gene and protein expressions associated with fibrosis and senescence, which could potentially affect hair follicle health and contribute to aging-related hair changes.

This study observed that different types of hairline recession increased the perceived facial age of East Asian males, with hair loss type C2 or U2 making those in their 30s appear significantly older.

This study found that inhibiting TGF-β receptors in adult dermal fibroblasts restored their function and increased resistance to Staphylococcus aureus infection by enhancing their adipogenic and antimicrobial capabilities.

This review discusses the age-related diagnostic challenges and comorbidities of polycystic ovarian syndrome and provides no new clinical findings; the authors emphasize the role of obesity in insulin resistance among affected women.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

This study found that as Japanese women age, their hair cuticle becomes more prone to damage, shifting from type L to type E damage patterns, and hair surface properties, including fatty acid content, deteriorate.

This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.

This article reviews the impact of aging and related urologic conditions on male fertility, highlighting the effects of various treatments on sperm parameters and recommending pre-treatment counseling for fertility preservation. It reports no new clinical results.

This study found that while the global incidence of alopecia areata in individuals aged 0–19 declined from 1990-2021, the total number of cases rose, with higher burdens among females, adolescents, and low-SDI populations, particularly in Central Sub-Saharan Africa; disparities suggest a need for targeted interventions.

This article discusses the management of pediatric alopecia areata in children aged 6 to 11, emphasizing the need for psychosocial support and limited medical treatments, as no systemic therapies are FDA-approved for this age group, despite the significant psychosocial burden.