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Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Oestrogens are key for bone growth during puberty in both boys and girls.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Aromatase gene variation may increase female hair loss risk.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Birth control pills increase the risk of blood clots, especially within the first year and with certain types.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.

Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

Chemotherapy causes hair loss starting soon after treatment begins and recovers about 3 months after ending, while tamoxifen does not significantly affect hair growth.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Fulvestrant at 10 mg/kg does not promote hair regrowth in dogs with alopecia X.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.