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This study found that ornithine decarboxylase (ODC) may play a significant role in regulating human hair growth and hair cycle changes, as inhibiting ODC reduced follicular keratinocyte proliferation and human hair growth.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

The researchers reported that repurposing the drug eflornithine may offer a treatment option for Bachmann-Bupp Syndrome, highlighting a potential model for other rare diseases.

In this placebo-controlled clinical study, a cream containing 4% capryloyl glycine and 1% glycine soy‐fermented extract effectively inhibited ODC1 activity and improved hypertrichosis in 91.7% of Caucasian female patients on the forearms, whereas no improvement was observed with the placebo.

This study reported that overexpressing ornithine decarboxylase in C57Bl/6 mice increased their sensitivity to tumor promotion by TPA, a change reversible by doxycycline treatment.

This study found that overexpression of antizyme in mice with activated MEK reduced skin tumor growth by inhibiting putrescine accumulation, slowing cell growth, and increasing G2/M transit time.

The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.

This study found that patients with Bachmann-Bupp syndrome treated with DFMO showed improvements in hair growth, muscle tone, and development.

Higher thyroid hormone levels may be linked to certain types of polycystic ovary syndrome.

This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.

This study found that Hairless (HR) and putrescine form a negative regulatory network that impacts epidermal homeostasis and hair follicle cycling, linked to the MYC superfamily's regulation of ODC expression.

This study reported that high ornithine decarboxylase expression and decreased keratin K1 and K10 expression may serve as useful markers for early stages of tumor development in mouse skin.

This study found that plucking hair from rats' dorsal skin rapidly decreased ornithine decarboxylase activity, possibly due to an inhibitory substance that was activated by ammonium sulfate treatment.

This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.

This study observed that hair regrowth in mice was irregular and delayed more in older mice, with increased enzyme activities in hair re-growing areas compared to non-growing areas.

This study found that overexpression of antizyme in MEK-activated transgenic mice reduced skin tumor development and restored normal differentiation of keratinocyte progenitor cells, highlighting the role of polyamines in keratinocyte biology.

This study reports that patients with Alzheimer's disease have increased levels of polyamines in their hair.

This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.

This study found that the hairless gene in mice has a more extensive role in development than previously thought, as indicated by its expression in various tissues and associated abnormalities in hr/hr mutants.

This study found that polyamines enhance genome integrity by facilitating homologous recombination-mediated DNA repair, suggesting a novel role for polyamines beyond promoting cell growth and proliferation.

In this study, topical application of α-methylspermidine during the telogen phase in mice induced hair growth by increasing the polyamine pool and mimicking the anagen phase's characteristics.

Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.

This review discusses recent developments in dermatological treatments for skin conditions such as acne, psoriasis, acute inflammation, and alopecia but reports no new clinical results.

This review discusses the role of Demodex mites in ocular demodecosis and various eye ailments, highlighting diagnostic methods but noting a lack of standardized treatments, with no new clinical results reported.

In this study, researchers used a CRISPR-based method to correct mutations in the COL7A1 gene in stem cells from RDEB patients, restoring normal collagen expression in engineered skin grafts in mice.

In this study, oral spermidine supplementation was found to significantly prolong the hair follicle anagen phase and reduce hair loss, with effects persisting three months after treatment in healthy participants, suggesting potential therapeutic benefits for hair loss conditions.

This study found that mosaic mutations in the CARD14 gene are linked to inflammatory linear verrucous epidermal naevus in two patients, who experienced significant improvement with the IL12/IL23 inhibitor Ustekinumab.

This study suggests that subtle modifications in ribosomal RNA methylation may influence cellular physiology and contribute to ribosome specialization in senescent human dermal fibroblasts.

This study found that polyamine levels were higher in the vertex hair than in occipital hair among patients with pattern baldness, suggesting a relation to hair loss development in the scalp's vertex region.