33 citations
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January 1979 in “Acta obstetricia et gynecologica Scandinavica” This study found that Diane®, a combination of cyproterone acetate and ethinyl estradiol, is an effective contraceptive and treatment for acne and seborrhea, but less effective for pronounced hair growth.
March 2002 in “Reactions Weekly” Some birth control pills increase blood clot risk; use them for specific conditions only.
1514 citations
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December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.
991 citations
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January 2011 in “Nature Reviews Endocrinology” This paper reviews the diagnostic criteria, associated morbidities, and possible evolutionary advantages of polycystic ovary syndrome, but does not report any new findings.
441 citations
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May 2008 in “British Journal of Pharmacology” This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.
403 citations
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November 2005 in “Journal of Endocrinology” This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.
305 citations
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February 2007 in “Hormone and metabolic research” This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
233 citations
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November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
research Acne
231 citations
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April 2005 in “The New England Journal of Medicine” This article discusses the treatment considerations for a 17-year-old boy with a six-month history of acne but reports no new research findings.
205 citations
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July 2009 in “Journal of Dermatological Science” This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.
169 citations
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August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” This article discusses treatments for hirsutism and acne in women with polycystic ovary syndrome, suggesting that lower doses of current medications maintain efficacy while reducing cost and side effects, but reports no new clinical results.
158 citations
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February 2000 in “Archives of dermatology” This study reports that some patients with androgenetic alopecia may also exhibit clinical and histological features of inflammation and fibrosis, similar to those found in lichen planopilaris.
118 citations
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September 2004 in “Clinics in Dermatology” This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.
117 citations
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February 2017 in “American Journal of Clinical Dermatology” This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
96 citations
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September 2008 in “Seminars in Cutaneous Medicine and Surgery” This review discusses the hormonal influences on acne's development in women and the therapeutic potential of hormonal treatments, but it reports no new clinical results.
89 citations
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November 2014 in “Medical Clinics of North America” This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.
87 citations
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March 2000 in “American Journal of Clinical Dermatology” Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
81 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” This review discusses the classifications, diagnostic methods, and treatment strategies for female pattern hair loss, but reports no clinical results.
76 citations
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December 2009 in “Clinics in Dermatology” This review discusses the indications, contraindications, and potential for using hormonal therapy as a first-line treatment for acne in females, but reports no new clinical results.
76 citations
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January 2007 in “American Journal of Clinical Dermatology” This review discusses the dermatologic features of PCOS as potential early indicators of the syndrome and notes that treatment of these conditions may enhance quality of life and psychological well-being, but it reports no new clinical results.
75 citations
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June 1999 in “Pediatric Clinics of North America” This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.
67 citations
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September 2008 in “Dermatologic therapy” This paper reviews causes of hirsutism in women and emphasizes the importance of identifying underlying conditions for risk assessment, though it reports no new clinical findings.
67 citations
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July 2006 in “Clinics in Dermatology” This review discusses the dermatologic manifestations of hyperandrogenism in women and outlines the diagnostic approach and treatment options, reporting no new clinical results.
66 citations
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June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
63 citations
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March 1995 in “International Journal of Dermatology” Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.
57 citations
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January 1995 in “The American journal of medicine” This study discusses the use of oral contraceptives as a treatment for hyperandrogenism, showing improvement in hirsutism and acne for many women and possibly providing metabolic benefits with certain formulations.
56 citations
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October 1983 in “Archives of Dermatology” This study found that free testosterone levels were a more sensitive indicator of hyperandrogenism in women with acne than total testosterone levels.
51 citations
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September 2015 in “Medical Clinics of North America” This review discusses common skin appendage diseases, including their pathophysiology and treatments, but does not report new results.
50 citations
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May 2020 in “Journal of Clinical Medicine” This review highlights the need for tailored hormonal treatment strategies for non-binary transgender individuals, emphasizing personalized care to enhance psychological well-being and quality of life.