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Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Ectoin helps prevent cortisone-induced skin problems and supports skin health.

The glucocorticoid receptor helps protect skin from tumors and other issues.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Excess androgens may cause PCOS, not just be a symptom.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.