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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Oral methylprednisolone pulse therapy helped an 11-year-old regrow 80% of his hair in six months.

Corticosteroid pulse therapy is more effective for severe alopecia areata than combination therapy.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Testosterone is crucial for development, growth, and various body functions in mammals.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

The document explains how male reproductive hormones work and affect the body.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.