1 citations
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July 2019 in “Farmatsevtychnyĭ zhurnal” This study developed an optimal gel-mask composition with nettle juice intended for treating telogen effluvium, determining the ideal concentrations for antioxidants and preservatives through extensive rheological and microbiological testing.
January 2018 in “journal of applied pharmaceutical science” This study found that biomimetic peptides may enhance the expression of growth factors in the hair follicles of patients experiencing telogen effluvium.
8 citations
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May 2017 in “Current traditional medicine” This review explores the phytochemistry and phytopharmacology of Urtica dioica but reports no new experimental findings, focusing on its traditional uses and range of bioactive constituents.
In this study, Urtica dioica L. infusions were used to replace water in k-carrageenan hydrogels, resulting in stronger networks with reduced syneresis and altered textural properties, and the highest antioxidant potential was achieved with specific infusion conditions.
26 citations
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January 2002 in “Advances in experimental medicine and biology” This article reviews the historical context of finasteride's development for BPH and its serendipitous discovery for hair growth, reporting no new research outcomes.
3 citations
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October 2018 in “Revista de Chimie” This review discusses the potential medicinal properties and pharmacokinetic features of nettle compounds ursolic acid and quercetin, highlighting quercetin as a promising candidate for antioxidant and anti-aging effects, but reports no new clinical results.
1 citations
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January 2023 in “PubMed” In this study, Urtica dioica extract was found to significantly downregulate 5-alpha-reductase type II gene expression in skin cells, suggesting potential usefulness against androgenic skin diseases.
1 citations
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September 2017 in “Revista de la Sociedad Química del Perú” This study found that a shampoo containing 2% alcohol extract of Urtica urens L. reduced hair loss by 56.8% in individuals with non-pathological hair loss after 21 days.
This study reviews the use of natural products, like herbal extracts and essential oils, in treating male pattern baldness, noting their potential benefits compared to conventional therapies that may carry side effects or ethical concerns.
The authors discussed the potential benefits of Urtica dioica and Serenoa repens for hair health, but emphasized that more concrete evidence and standardized formulations are necessary for reliable therapeutic use.
May 2025 in “Frontiers in Bioinformatics” This study used computational methods to identify six molecules, with jamogenin being particularly promising, that effectively bind to and inhibit the enzyme linked to male pattern hair loss, suggesting these compounds could be explored further for hair growth potential.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, computational analysis identified six molecules, including Jamogenin, as effective in binding to the enzyme 5-alpha reductase (5-AR) from herbal extracts like nettle, saw palmetto, and fenugreek, suggesting potential for hair loss treatments.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers used computational methods to identify six phytochemicals from nettle, saw palmetto, and fenugreek as effective binders to 5-alpha reductase, with Jamogenin showing enhanced stability when encapsulated in lipid nanoparticles.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study identified six molecules from herbal extracts that effectively bind to 5-alpha reductase (5-AR), with Jomogenin showing high binding stability when encapsulated in lipid nanoparticles, suggesting their potential for further experimental analysis to aid hair follicle growth.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this computational study, researchers identified six phytochemicals, including Jamogenin, that effectively bind to the enzyme 5-AR, potentially promoting hair growth, and found that encapsulating Jamogenin in lipid nanoparticles enhances its stability.
July 2024 in “Journal of Eastern – Western Pharmacology and Pharmacy” This study found that Tribulus terrestris L. extract promoted significant hair growth and reduced skin inflammation in Wistar rats, while Urtica cannabina extract, Glycyrrhiza glabra extract, and Tribulus terrestris L. extract all led to uniform hair growth over 28 days compared to other tested extracts.
February 2024 in “Cosmetics” In this study, researchers developed a novel platform for discovering potential hair loss inhibitors by investigating the testosterone/dihydrotestosterone biosynthetic pathway and its regulation through biochemical mechanisms involving 17β-HSD and 3β-HSD, combined with medicinal plant extracts.
March 2018 in “Klìnìčna farmacìâ” This study outlines a methodological approach for developing dermato-cosmetic remedies using natural raw materials that may aid in the prevention and treatment of androgenic alopecia and telogen effluvium.
January 2018 in “Turkiye Klinikleri Journal of Dermatology” This study identified the most common plants in hair cosmetics, like shampoos and dyes, with Rosmarinus officinalis L. and Lawsonia inermis L. leading, to serve as a reference for future research and healthcare professionals.
September 1997 in “Bulletin of the history of medicine” This review discusses the potential for discovering new drugs in ancient and medieval European texts and reports no new clinical research, emphasizing the need for scientific exploration of historical medicinal knowledge.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
July 2019 in “Technology audit and production reserves” This research discusses the formulation of probiotic gel shampoos with whey peptides and plant extracts, highlighting their potential effectiveness and market feasibility in Ukraine.
September 2018 in “Central Asian journal of medical sciences (Print)” This study found that Urticadioica L ethanol extracts enhanced hair growth and reduced catagen transition in human hair follicles in an ex vivo organ culture model.
March 2018 in “Farmacevtičnij časopis” In this study, researchers developed an optimized production process for the herbal tincture "Stimufit," intended for topical use in treating telogen alopecia, using 40% ethanol and a specific extraction method.
This study reported that a shampoo containing alcoholic extract of Urtica urens L. was effective in reducing hair loss by over 50% without causing skin irritability.
January 2015 in “Farmatsevtychnyĭ zhurnal” This research discusses the development of a complex tincture for telogen effluvium using nettle, sage, and chestnut leaves, but provides no new clinical results.
In a laboratory setting, this study reported that the n-butanol fraction of Urtica laetevirens Maxim. water extracts significantly inhibited 5α-reductase activity.
January 2009 in “Lishizhen Medicine and Materia Medica Research” The researchers reported that the aqueous extract of Urtica fissa E.Pritz inhibited 5α-reductase activity in vitro.
March 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This article discusses various synthetic and herbal treatments for alopecia, noting limited effectiveness and associated side effects of synthetic options, and reports no new clinical results.
69 citations
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July 1997 in “Der Urologe” This study found that PRO 160/120 and Finasteride showed similar effectiveness in improving urinary symptoms and quality of life in patients with benign prostatic hyperplasia over 48 weeks.