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    Glossary Nerve Growth Factor

    protein promoting nerve cell growth and survival

    Nerve Growth Factor (NGF) is a protein that plays a crucial role in the growth, maintenance, and survival of nerve cells, including those in the brain. It is essential for the development of the nervous system and has been studied for its potential in treating neurodegenerative diseases and promoting hair growth by supporting the health of hair follicles.

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    1. Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor American Journal of Pathology · 2004 · 108 citations
    2. Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways Journal of Molecular Medicine · 2007 · 66 citations
    3. Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells Burns · 2023 · 11 citations
    4. Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons. The Journal of Cell Biology · 1993 · 5 citations
    5. Nerve growth factor regulates the proliferation of cashmere goat outer root sheath cells through the activation of cAMP-binding protein Small ruminant research · 2019 · 1 citations
    6. Expression of nerve growth factor in skin tissues and its effect on the proliferation of outer root sheath cells in cashmere goats Livestock science · 2016 · 1 citations
    7. Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer’s Disease Journal of Integrative Neuroscience · 2026
    8. 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration Biomedicines · 2022
    9. Increased expression of nerve growth factor and neurokinin-1 alarm the hair loss in female with trichodynia Journal of The American Academy of Dermatology · 2012
    10. Neurogenic skin inflammation in stress‐triggered inhibition of hair growth in mice is promoted via nerve growth factor‐dependent pathways Experimental Dermatology · 2004
    11. Epidermal Growth Factor Receptor Regulates Skin Nerve Outgrowth and Branching Journal of Investigative Dermatology · 2009
    12. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    13. An Overview of Growth Factors as the Potential Link between Psoriasis and Metabolic Syndrome Journal of Clinical Medicine · 2023 · 6 citations
    14. ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators Experimental dermatology · 2006
    15. The study of the altering of cytokines and growth factors secreted by cultured balding dermal papilla cells 2012
    16. Brain-derived nerve factor and neurotrophins in androgenetic alopecia British Journal of Dermatology · 2011 · 10 citations
    17. Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control Experimental Dermatology · 2005 · 127 citations
    18. Epithelial growth control by neurotrophins: leads and lessons from the hair follicle Progress in brain research · 2004 · 99 citations
    19. Cyclosporine A stimulated hair growth from mouse vibrissae follicles in an organ culture model Journal of Nanjing Medical University · 2012 · 11 citations
    20. Inhibitory Effects of Polyacetylene Compounds from <i>Panax ginseng</i> on Neurotrophin Receptor-Mediated Hair Growth Biological & Pharmaceutical Bulletin · 2017 · 7 citations
    21. Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro PLOS ONE · 2019 · 6 citations
    22. Research progress on the role of peripheral nerves in wound healing Journal of Zhejiang University (Medical Sciences) · 2025
    23. Psychological stress impact neurotrophic factor levels in patients with androgenetic alopecia and correlated with disease progression World Journal of Psychiatry · 2024
    24. Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin International journal of molecular sciences · 2024
    25. Secretome of Mesenchymal Stromal Cells as a Possible Innovative Therapeutic Tool in Facial Nerve Injury Treatment BioMed Research International · 2023 · 2 citations
    26. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006 · 375 citations
    27. Neuroimmunoendocrine circuitry of the ‘brain-skin connection’ Trends in Immunology · 2005 · 293 citations
    28. Neurotrophins, nociceptors, and pain Microscopy Research and Technique · 1999 · 189 citations
    29. Probing the Effects of Stress Mediators on the Human Hair Follicle American Journal of Pathology · 2007 · 159 citations
    30. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. PubMed · 1998 · 122 citations