41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
3 citations,
August 2018 in “Stem cells international” Hair follicle cells help maintain and support stem cells and blood cell formation.
39 citations,
January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
April 2017 in “Journal of Investigative Dermatology” PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
April 2017 in “Journal of Investigative Dermatology” Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
7 citations,
July 2014 in “BMJ case reports” A rare skin disorder, Ichthyosis with confetti, has no cure but treatment focuses on managing symptoms with moisturizers.
51 citations,
August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
21 citations,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
January 2022 in “Stem cell biology and regenerative medicine” Dermal sheath cells can help grow new hair follicles and show promise in treating hair loss.
11 citations,
August 2019 in “Journal of Molecular Histology” NFIC helps rat dental cells grow and turn into bone-like cells.
2 citations,
November 2015 in “Journal of Investigative Dermatology” RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.
Different types of skin cells and immune cells play a role in healing UV-damaged skin, with chronic UV exposure causing lasting damage to certain skin cells.
15 citations,
May 2003 in “The Laryngoscope” FGF-1 causes spiral ganglion neurites to branch more.
8 citations,
January 2016 in “Cells tissues organs” Norepinephrine helps skin cells grow, which is important for hair growth.
4 citations,
May 2012 in “BMJ Case Reports” A Nigerian baby with neonatal lupus got better with treatment by 6 months.
249 citations,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
69 citations,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
359 citations,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
68 citations,
August 2014 in “Stem Cells Translational Medicine” Dermal papilla cells help wounds heal better and can potentially grow new hair.
April 2018 in “Journal of Investigative Dermatology” Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
5 citations,
January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
56 citations,
September 2013 in “Experimental Dermatology” The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
18 citations,
January 2020 in “Acta dermato-venereologica” Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
12 citations,
August 2018 in “Journal of Dermatological Science” Scientists made stem cells that can grow hair by adding three specific factors to them.
3 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.