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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Low iron and vitamin D levels are linked to hair loss in women.

Certain drugs that block specific enzymes can help treat prostate diseases.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Human amniotic membrane helps heal skin wounds faster and with less scarring.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Women with PCOS have more emotional and body image issues than healthy women.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Some chemicals absorbed through the skin can cause serious health problems.