January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study investigated an herbal hair oil and shampoo formulation incorporating onion, neem, and flaxseed extracts, finding it effectively reduces hair fall and provides antifungal and conditioning benefits, thus offering a natural alternative to synthetic hair care products.
January 2025 in “Annals of Dermatology” In this nationwide cross-sectional study, researchers found that COVID-19 vaccination was associated with an increased risk of hair loss disorders, including total alopecia, alopecia areata, and telogen effluvium, while no significant link was observed between COVID-19 infection and these conditions.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated an herbal hair oil and shampoo made from onion, neem, and flaxseed extracts, finding that this natural formulation effectively addresses hair fall, offers antifungal benefits, and provides conditioning properties, presenting a stable and eco-friendly alternative to synthetic products.
January 2025 in “The Egyptian Journal of Hospital Medicine” This study found that keloid patients exhibited significantly higher expression levels of NEDD4-TV3 and IGF-1 genes compared to controls, indicating a potential role of these genes in predicting and understanding keloid formation.
January 2025 in “Indian Journal of Dermatopathology and Diagnostic Dermatology” In this histopathology study of nevus sebaceus, researchers observed distinct epidermal, sebaceous, follicular, and apocrine changes, including sebaceous hyperplasia and basaloid adnexal proliferation, which help differentiate it from similar conditions like basal cell carcinoma and trichoblastoma.
January 2025 in “International Journal of Dermatology Research” This study found that patients with alopecia areata had a significantly higher mean platelet volume compared to healthy individuals, suggesting a potential link between hematological markers and the severity of the disease.
This study found that exosomes derived from hair follicle neural crest stem cells significantly promoted nerve regeneration in injured neurons, particularly when overexpressing miR-214-3p, which enhanced axon extension and motor function recovery in both in vitro and in vivo models.
January 2025 in “International Journal of Advanced Biochemistry Research” This case report described a one-year-old male husky dog with severe itching and skin lesions caused by Demodex canis, where treatment with Nexgard® and other supportive therapies over two weeks improved the dog's condition, indicating Nexgard® as a viable option for managing canine demodicosis.
January 2025 in “Genetics in Medicine Open” This case report highlights a 33-year-old male initially misdiagnosed with Neuromyelitis Optica, whose symptoms may improve with biotin treatment due to late onset biotinidase deficiency.
November 2024 in “Journal of Cosmetic Dermatology” This study observed that a topical serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract enhanced hair follicle growth and hair shaft elongation, while prolonging the anagen phase in an ex vivo human scalp skin model, suggesting potential benefits for hair loss treatment.
November 2024 in “Journal of Investigative Dermatology” Reducing neutrophils or inhibiting NETs improves wound healing in sickle cell disease.
November 2024 in “Journal of Investigative Dermatology” In this study, UVB irradiation increased mast cell degranulation only when skin was innervated, suggesting that the interaction between mast cells and nerve fibres may exacerbate solar elastosis by promoting dysfunctional dermal elastic fiber accumulation, but further research is needed for confirmation.
November 2024 in “Journal of Investigative Dermatology” Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.
November 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that exosomes derived from bovine colostrum, compared to those from human stem cells, significantly increased hair follicle growth and regeneration in vitro.
November 2024 in “Human Cell” This study found that treating rat whisker follicle stem cells with retinoic acid and epidermal growth factor induced them to express synaptophysin, a marker of mature neurons, although there was a reduction in other neural markers, suggesting potential for neuro-regeneration applications.
October 2024 in “World Journal of Psychiatry” In this study, patients with androgenetic alopecia experiencing stress had higher cortisol levels and altered neurotrophic factors compared to non-stressed patients, which correlated with more severe hair loss progression even after minoxidil treatment.
September 2024 in “Egyptian Journal of Medical Human Genetics” This case report adds to the understanding of neurofibromatosis type 1 by documenting an Egyptian child with the condition alongside multiple unusual congenital anomalies, highlighting the importance of considering NF1 when these features are present.
September 2024 in “The Journal of Dermatology” In this study, researchers reported a rare case of nevus comedonicus with hair growth in a 26-year-old male, challenging prior reports that affected lesions typically lack the capability to develop terminal hair.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” This case report detailed a successful treatment involving contracture release and expanded neck flap reconstruction for a patient with severe neck contracture and beard alopecia from past thermal burns, highlighting improved skin quality and hair regrowth following follicular unit extraction.
September 2024 in “Advanced Biomedical Research” In this study, chick embryo extract enhanced neuronal differentiation and trophic factor expression in rat hair follicle stem cells, suggesting potential improvements for stem cell therapies in neurodegenerative diseases.
September 2024 in “Journal of the American Academy of Dermatology” This study reports that oxytocin receptor expression in keratinocytes shows a potential relationship with touch sensory neurons, suggesting a role in skin sensitivity and the broader function of sensory neurons.
August 2024 in “International Journal of Cosmetic Science” This study found that acetyl zingerone methyl ether (MAZ) in hair dyes and haircare products may reduce oxidative damage, improve hair condition, and enhance the longevity and quality of dyed hair color.
August 2024 in “Drug Design Development and Therapy” This review explores the biological applications and pharmacokinetics of decursin, a compound isolated from Angelica gigas, highlighting its potential neuroprotective, anti-inflammatory, and anticancer properties based on in vitro and in vivo studies.
July 2024 in “New Phytologist” This study suggests that the transcription factor PDF2 in Arabidopsis may link lipid sensing with growth responses to phosphate starvation by acting as a sensor for lyso-PCs through its START domain.
July 2024 in “Journal of Investigative Dermatology” Bioactive peptides improve graft survival and new hair growth.
July 2024 in “Journal of Investigative Dermatology” This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.
July 2024 in “Journal of Investigative Dermatology” In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.
July 2024 in “Journal of Investigative Dermatology” A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.
July 2024 in “Journal of Investigative Dermatology” In this study, baicalin, a component of Baikal skullcap, was found to inhibit necroptosis in a cellular model of toxic epidermal necrolysis, suggesting it may be effective against severe drug-induced skin eruptions.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.